3BAP
Crystal Structure of the 25 kDa Subunit of Human Cleavage Factor Im
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003682 | molecular_function | chromatin binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003729 | molecular_function | mRNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005813 | cellular_component | centrosome |
| A | 0005847 | cellular_component | mRNA cleavage and polyadenylation specificity factor complex |
| A | 0005849 | cellular_component | mRNA cleavage factor complex |
| A | 0006397 | biological_process | mRNA processing |
| A | 0010608 | biological_process | post-transcriptional regulation of gene expression |
| A | 0016604 | cellular_component | nuclear body |
| A | 0030154 | biological_process | cell differentiation |
| A | 0031124 | biological_process | mRNA 3'-end processing |
| A | 0035925 | molecular_function | mRNA 3'-UTR AU-rich region binding |
| A | 0042382 | cellular_component | paraspeckles |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0042826 | molecular_function | histone deacetylase binding |
| A | 0051262 | biological_process | protein tetramerization |
| A | 0051290 | biological_process | protein heterotetramerization |
| A | 0110104 | biological_process | mRNA alternative polyadenylation |
| A | 0180010 | biological_process | co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway |
| A | 1900365 | biological_process | obsolete positive regulation of mRNA polyadenylation |
| A | 2000738 | biological_process | positive regulation of stem cell differentiation |
| A | 2000975 | biological_process | positive regulation of pro-B cell differentiation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2 |
| Chain | Residue |
| A | GLU81 |
| A | LYS105 |
| A | LEU106 |
| A | LYS172 |
| A | ILE211 |
| A | HOH237 |
| A | HOH317 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Region: {"description":"Interaction with RNA","evidences":[{"source":"PubMed","id":"20479262","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21295486","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MDG","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"3MDI","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"3Q2T","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with RNA","evidences":[{"source":"PubMed","id":"20479262","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MDG","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"3MDI","evidenceCode":"ECO:0000312"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17172643","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"15592455","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
