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3B6V

Crystal structure of the motor domain of human kinesin family member 3C in complex with ADP

Functional Information from GO Data
ChainGOidnamespacecontents
A0003777molecular_functionmicrotubule motor activity
A0005524molecular_functionATP binding
A0007018biological_processmicrotubule-based movement
A0008017molecular_functionmicrotubule binding
B0003777molecular_functionmicrotubule motor activity
B0005524molecular_functionATP binding
B0007018biological_processmicrotubule-based movement
B0008017molecular_functionmicrotubule binding
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 1002
ChainResidue
ATHR104
AADP1001
AHOH1006
AHOH1007
AHOH1008

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE MG B 1002
ChainResidue
BHOH1010
BHOH1013
BTHR104
BADP1001
BHOH1008
BHOH1009

site_idAC3
Number of Residues14
DetailsBINDING SITE FOR RESIDUE ADP A 1001
ChainResidue
AARG18
AGLN98
ATHR99
AGLY100
ATHR101
AGLY102
ALYS103
ATHR104
ATYR105
ATHR110
AMG1002
AHOH1006
AHOH1008
BTRP111

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE UNX A 1003
ChainResidue
AASP65
AALA66

site_idAC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE UNX A 1004
ChainResidue
AGLY331
AGLY332

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE UNX A 1005
ChainResidue
ATYR105
ATHR110
ATRP111
ALEU116

site_idAC7
Number of Residues15
DetailsBINDING SITE FOR RESIDUE ADP B 1001
ChainResidue
ATRP111
BARG18
BPRO19
BGLN98
BTHR99
BGLY100
BTHR101
BGLY102
BLYS103
BTHR104
BTYR105
BTHR110
BMG1002
BHOH1008
BHOH1013

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE UNX B 1003
ChainResidue
BTYR96
BGLY97
BALA248
BSER250

site_idAC9
Number of Residues5
DetailsBINDING SITE FOR RESIDUE UNX B 1004
ChainResidue
BARG16
BGLN70
BTHR106
BGLY118
BVAL119

site_idBC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE UNX B 1005
ChainResidue
BARG324
BLEU325
BGLN327
BASP328

site_idBC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE UNX B 1006
ChainResidue
BLYS56
BARG357

site_idBC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE UNX B 1007
ChainResidue
BALA10
BLYS335
BTHR336

Functional Information from PROSITE/UniProt
site_idPS00411
Number of Residues12
DetailsKINESIN_MOTOR_1 Kinesin motor domain signature. GKLnLVDLAGSE
ChainResidueDetails
AGLY240-GLU251

site_idPS00467
Number of Residues12
DetailsRIBOSOMAL_L2 Ribosomal protein L2 signature. PelRGVIpNAfE
ChainResidueDetails
APRO114-GLU125

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AGLY97
BGLY97

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1goj
ChainResidueDetails
AGLY249

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1goj
ChainResidueDetails
BGLY249

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PDB entries from 2024-11-13

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