3B6M
WrbA from Escherichia coli, second crystal form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003955 | molecular_function | NAD(P)H dehydrogenase (quinone) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0008753 | molecular_function | NADPH dehydrogenase (quinone) activity |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050136 | molecular_function | NADH:ubiquinone reductase (non-electrogenic) activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003955 | molecular_function | NAD(P)H dehydrogenase (quinone) activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0008753 | molecular_function | NADPH dehydrogenase (quinone) activity |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016020 | cellular_component | membrane |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0032991 | cellular_component | protein-containing complex |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050136 | molecular_function | NADH:ubiquinone reductase (non-electrogenic) activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE FMN A 200 |
| Chain | Residue |
| A | SER10 |
| A | PHE80 |
| A | ASP92 |
| A | SER113 |
| A | THR114 |
| A | GLY115 |
| A | THR116 |
| A | GLY117 |
| A | GLY118 |
| A | HIS133 |
| A | 144201 |
| A | MET11 |
| A | HOH216 |
| A | TYR12 |
| A | GLY13 |
| A | HIS14 |
| A | ILE15 |
| A | PRO77 |
| A | THR78 |
| A | ARG79 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FMN B 200 |
| Chain | Residue |
| B | SER10 |
| B | MET11 |
| B | TYR12 |
| B | GLY13 |
| B | HIS14 |
| B | ILE15 |
| B | PRO77 |
| B | THR78 |
| B | ARG79 |
| B | PHE80 |
| B | ASP92 |
| B | SER113 |
| B | THR114 |
| B | GLY115 |
| B | THR116 |
| B | GLY117 |
| B | GLY118 |
| B | HIS133 |
| B | 144201 |
| B | HOH250 |
| B | HOH311 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 144 A 201 |
| Chain | Residue |
| A | TRP98 |
| A | THR116 |
| A | GLY118 |
| A | HIS133 |
| A | FMN200 |
| B | TYR143 |
| B | PRO159 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 144 B 201 |
| Chain | Residue |
| A | TYR143 |
| A | GLN146 |
| A | PRO159 |
| B | TRP98 |
| B | THR116 |
| B | GLY118 |
| B | HIS133 |
| B | FMN200 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 15P A 202 |
| Chain | Residue |
| A | TYR188 |
| A | GLY191 |
| A | LEU192 |
| A | LYS195 |
| A | HOH213 |
| B | GLY105 |
| B | LEU196 |
| B | ASN197 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01017, ECO:0000269|PubMed:17951395, ECO:0000269|PubMed:19665595 |
| Chain | Residue | Details |
| A | SER10 | |
| A | THR78 | |
| A | SER113 | |
| A | HIS133 | |
| B | SER10 | |
| B | THR78 | |
| B | SER113 | |
| B | HIS133 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17951395 |
| Chain | Residue | Details |
| A | TYR12 | |
| A | ALA51 | |
| A | ASP169 | |
| B | TYR12 | |
| B | ALA51 | |
| B | ASP169 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01017, ECO:0000305|PubMed:17951395 |
| Chain | Residue | Details |
| A | TRP98 | |
| B | TRP98 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842 |
| Chain | Residue | Details |
| A | LYS50 | |
| B | LYS50 |
