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3B5U

Actin filament model from extended form of acromsomal bundle in the Limulus sperm

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000287molecular_functionmagnesium ion binding
A0001725cellular_componentstress fiber
A0003785molecular_functionactin monomer binding
A0005509molecular_functioncalcium ion binding
A0005515molecular_functionprotein binding
A0005523molecular_functiontropomyosin binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005856cellular_componentcytoskeleton
A0005865cellular_componentstriated muscle thin filament
A0005884cellular_componentactin filament
A0010628biological_processpositive regulation of gene expression
A0016787molecular_functionhydrolase activity
A0019904molecular_functionprotein domain specific binding
A0030027cellular_componentlamellipodium
A0030041biological_processactin filament polymerization
A0030175cellular_componentfilopodium
A0030240biological_processskeletal muscle thin filament assembly
A0031013molecular_functiontroponin I binding
A0031432molecular_functiontitin binding
A0031941cellular_componentfilamentous actin
A0032036molecular_functionmyosin heavy chain binding
A0032432cellular_componentactin filament bundle
A0042802molecular_functionidentical protein binding
A0044297cellular_componentcell body
A0048306molecular_functioncalcium-dependent protein binding
A0048741biological_processskeletal muscle fiber development
A0051017biological_processactin filament bundle assembly
A0090131biological_processmesenchyme migration
A0098723cellular_componentskeletal muscle myofibril
A0140660molecular_functioncytoskeletal motor activator activity
B0000166molecular_functionnucleotide binding
B0000287molecular_functionmagnesium ion binding
B0001725cellular_componentstress fiber
B0003785molecular_functionactin monomer binding
B0005509molecular_functioncalcium ion binding
B0005515molecular_functionprotein binding
B0005523molecular_functiontropomyosin binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0005865cellular_componentstriated muscle thin filament
B0005884cellular_componentactin filament
B0010628biological_processpositive regulation of gene expression
B0016787molecular_functionhydrolase activity
B0019904molecular_functionprotein domain specific binding
B0030027cellular_componentlamellipodium
B0030041biological_processactin filament polymerization
B0030175cellular_componentfilopodium
B0030240biological_processskeletal muscle thin filament assembly
B0031013molecular_functiontroponin I binding
B0031432molecular_functiontitin binding
B0031941cellular_componentfilamentous actin
B0032036molecular_functionmyosin heavy chain binding
B0032432cellular_componentactin filament bundle
B0042802molecular_functionidentical protein binding
B0044297cellular_componentcell body
B0048306molecular_functioncalcium-dependent protein binding
B0048741biological_processskeletal muscle fiber development
B0051017biological_processactin filament bundle assembly
B0090131biological_processmesenchyme migration
B0098723cellular_componentskeletal muscle myofibril
B0140660molecular_functioncytoskeletal motor activator activity
C0000166molecular_functionnucleotide binding
C0000287molecular_functionmagnesium ion binding
C0001725cellular_componentstress fiber
C0003785molecular_functionactin monomer binding
C0005509molecular_functioncalcium ion binding
C0005515molecular_functionprotein binding
C0005523molecular_functiontropomyosin binding
C0005524molecular_functionATP binding
C0005737cellular_componentcytoplasm
C0005856cellular_componentcytoskeleton
C0005865cellular_componentstriated muscle thin filament
C0005884cellular_componentactin filament
C0010628biological_processpositive regulation of gene expression
C0016787molecular_functionhydrolase activity
C0019904molecular_functionprotein domain specific binding
C0030027cellular_componentlamellipodium
C0030041biological_processactin filament polymerization
C0030175cellular_componentfilopodium
C0030240biological_processskeletal muscle thin filament assembly
C0031013molecular_functiontroponin I binding
C0031432molecular_functiontitin binding
C0031941cellular_componentfilamentous actin
C0032036molecular_functionmyosin heavy chain binding
C0032432cellular_componentactin filament bundle
C0042802molecular_functionidentical protein binding
C0044297cellular_componentcell body
C0048306molecular_functioncalcium-dependent protein binding
C0048741biological_processskeletal muscle fiber development
C0051017biological_processactin filament bundle assembly
C0090131biological_processmesenchyme migration
C0098723cellular_componentskeletal muscle myofibril
C0140660molecular_functioncytoskeletal motor activator activity
D0000166molecular_functionnucleotide binding
D0000287molecular_functionmagnesium ion binding
D0001725cellular_componentstress fiber
D0003785molecular_functionactin monomer binding
D0005509molecular_functioncalcium ion binding
D0005515molecular_functionprotein binding
D0005523molecular_functiontropomyosin binding
D0005524molecular_functionATP binding
D0005737cellular_componentcytoplasm
D0005856cellular_componentcytoskeleton
D0005865cellular_componentstriated muscle thin filament
D0005884cellular_componentactin filament
D0010628biological_processpositive regulation of gene expression
D0016787molecular_functionhydrolase activity
D0019904molecular_functionprotein domain specific binding
D0030027cellular_componentlamellipodium
D0030041biological_processactin filament polymerization
D0030175cellular_componentfilopodium
D0030240biological_processskeletal muscle thin filament assembly
D0031013molecular_functiontroponin I binding
D0031432molecular_functiontitin binding
D0031941cellular_componentfilamentous actin
D0032036molecular_functionmyosin heavy chain binding
D0032432cellular_componentactin filament bundle
D0042802molecular_functionidentical protein binding
D0044297cellular_componentcell body
D0048306molecular_functioncalcium-dependent protein binding
D0048741biological_processskeletal muscle fiber development
D0051017biological_processactin filament bundle assembly
D0090131biological_processmesenchyme migration
D0098723cellular_componentskeletal muscle myofibril
D0140660molecular_functioncytoskeletal motor activator activity
E0000166molecular_functionnucleotide binding
E0000287molecular_functionmagnesium ion binding
E0001725cellular_componentstress fiber
E0003785molecular_functionactin monomer binding
E0005509molecular_functioncalcium ion binding
E0005515molecular_functionprotein binding
E0005523molecular_functiontropomyosin binding
E0005524molecular_functionATP binding
E0005737cellular_componentcytoplasm
E0005856cellular_componentcytoskeleton
E0005865cellular_componentstriated muscle thin filament
E0005884cellular_componentactin filament
E0010628biological_processpositive regulation of gene expression
E0016787molecular_functionhydrolase activity
E0019904molecular_functionprotein domain specific binding
E0030027cellular_componentlamellipodium
E0030041biological_processactin filament polymerization
E0030175cellular_componentfilopodium
E0030240biological_processskeletal muscle thin filament assembly
E0031013molecular_functiontroponin I binding
E0031432molecular_functiontitin binding
E0031941cellular_componentfilamentous actin
E0032036molecular_functionmyosin heavy chain binding
E0032432cellular_componentactin filament bundle
E0042802molecular_functionidentical protein binding
E0044297cellular_componentcell body
E0048306molecular_functioncalcium-dependent protein binding
E0048741biological_processskeletal muscle fiber development
E0051017biological_processactin filament bundle assembly
E0090131biological_processmesenchyme migration
E0098723cellular_componentskeletal muscle myofibril
E0140660molecular_functioncytoskeletal motor activator activity
F0000166molecular_functionnucleotide binding
F0000287molecular_functionmagnesium ion binding
F0001725cellular_componentstress fiber
F0003785molecular_functionactin monomer binding
F0005509molecular_functioncalcium ion binding
F0005515molecular_functionprotein binding
F0005523molecular_functiontropomyosin binding
F0005524molecular_functionATP binding
F0005737cellular_componentcytoplasm
F0005856cellular_componentcytoskeleton
F0005865cellular_componentstriated muscle thin filament
F0005884cellular_componentactin filament
F0010628biological_processpositive regulation of gene expression
F0016787molecular_functionhydrolase activity
F0019904molecular_functionprotein domain specific binding
F0030027cellular_componentlamellipodium
F0030041biological_processactin filament polymerization
F0030175cellular_componentfilopodium
F0030240biological_processskeletal muscle thin filament assembly
F0031013molecular_functiontroponin I binding
F0031432molecular_functiontitin binding
F0031941cellular_componentfilamentous actin
F0032036molecular_functionmyosin heavy chain binding
F0032432cellular_componentactin filament bundle
F0042802molecular_functionidentical protein binding
F0044297cellular_componentcell body
F0048306molecular_functioncalcium-dependent protein binding
F0048741biological_processskeletal muscle fiber development
F0051017biological_processactin filament bundle assembly
F0090131biological_processmesenchyme migration
F0098723cellular_componentskeletal muscle myofibril
F0140660molecular_functioncytoskeletal motor activator activity
G0000166molecular_functionnucleotide binding
G0000287molecular_functionmagnesium ion binding
G0001725cellular_componentstress fiber
G0003785molecular_functionactin monomer binding
G0005509molecular_functioncalcium ion binding
G0005515molecular_functionprotein binding
G0005523molecular_functiontropomyosin binding
G0005524molecular_functionATP binding
G0005737cellular_componentcytoplasm
G0005856cellular_componentcytoskeleton
G0005865cellular_componentstriated muscle thin filament
G0005884cellular_componentactin filament
G0010628biological_processpositive regulation of gene expression
G0016787molecular_functionhydrolase activity
G0019904molecular_functionprotein domain specific binding
G0030027cellular_componentlamellipodium
G0030041biological_processactin filament polymerization
G0030175cellular_componentfilopodium
G0030240biological_processskeletal muscle thin filament assembly
G0031013molecular_functiontroponin I binding
G0031432molecular_functiontitin binding
G0031941cellular_componentfilamentous actin
G0032036molecular_functionmyosin heavy chain binding
G0032432cellular_componentactin filament bundle
G0042802molecular_functionidentical protein binding
G0044297cellular_componentcell body
G0048306molecular_functioncalcium-dependent protein binding
G0048741biological_processskeletal muscle fiber development
G0051017biological_processactin filament bundle assembly
G0090131biological_processmesenchyme migration
G0098723cellular_componentskeletal muscle myofibril
G0140660molecular_functioncytoskeletal motor activator activity
H0000166molecular_functionnucleotide binding
H0000287molecular_functionmagnesium ion binding
H0001725cellular_componentstress fiber
H0003785molecular_functionactin monomer binding
H0005509molecular_functioncalcium ion binding
H0005515molecular_functionprotein binding
H0005523molecular_functiontropomyosin binding
H0005524molecular_functionATP binding
H0005737cellular_componentcytoplasm
H0005856cellular_componentcytoskeleton
H0005865cellular_componentstriated muscle thin filament
H0005884cellular_componentactin filament
H0010628biological_processpositive regulation of gene expression
H0016787molecular_functionhydrolase activity
H0019904molecular_functionprotein domain specific binding
H0030027cellular_componentlamellipodium
H0030041biological_processactin filament polymerization
H0030175cellular_componentfilopodium
H0030240biological_processskeletal muscle thin filament assembly
H0031013molecular_functiontroponin I binding
H0031432molecular_functiontitin binding
H0031941cellular_componentfilamentous actin
H0032036molecular_functionmyosin heavy chain binding
H0032432cellular_componentactin filament bundle
H0042802molecular_functionidentical protein binding
H0044297cellular_componentcell body
H0048306molecular_functioncalcium-dependent protein binding
H0048741biological_processskeletal muscle fiber development
H0051017biological_processactin filament bundle assembly
H0090131biological_processmesenchyme migration
H0098723cellular_componentskeletal muscle myofibril
H0140660molecular_functioncytoskeletal motor activator activity
I0000166molecular_functionnucleotide binding
I0000287molecular_functionmagnesium ion binding
I0001725cellular_componentstress fiber
I0003785molecular_functionactin monomer binding
I0005509molecular_functioncalcium ion binding
I0005515molecular_functionprotein binding
I0005523molecular_functiontropomyosin binding
I0005524molecular_functionATP binding
I0005737cellular_componentcytoplasm
I0005856cellular_componentcytoskeleton
I0005865cellular_componentstriated muscle thin filament
I0005884cellular_componentactin filament
I0010628biological_processpositive regulation of gene expression
I0016787molecular_functionhydrolase activity
I0019904molecular_functionprotein domain specific binding
I0030027cellular_componentlamellipodium
I0030041biological_processactin filament polymerization
I0030175cellular_componentfilopodium
I0030240biological_processskeletal muscle thin filament assembly
I0031013molecular_functiontroponin I binding
I0031432molecular_functiontitin binding
I0031941cellular_componentfilamentous actin
I0032036molecular_functionmyosin heavy chain binding
I0032432cellular_componentactin filament bundle
I0042802molecular_functionidentical protein binding
I0044297cellular_componentcell body
I0048306molecular_functioncalcium-dependent protein binding
I0048741biological_processskeletal muscle fiber development
I0051017biological_processactin filament bundle assembly
I0090131biological_processmesenchyme migration
I0098723cellular_componentskeletal muscle myofibril
I0140660molecular_functioncytoskeletal motor activator activity
J0000166molecular_functionnucleotide binding
J0000287molecular_functionmagnesium ion binding
J0001725cellular_componentstress fiber
J0003785molecular_functionactin monomer binding
J0005509molecular_functioncalcium ion binding
J0005515molecular_functionprotein binding
J0005523molecular_functiontropomyosin binding
J0005524molecular_functionATP binding
J0005737cellular_componentcytoplasm
J0005856cellular_componentcytoskeleton
J0005865cellular_componentstriated muscle thin filament
J0005884cellular_componentactin filament
J0010628biological_processpositive regulation of gene expression
J0016787molecular_functionhydrolase activity
J0019904molecular_functionprotein domain specific binding
J0030027cellular_componentlamellipodium
J0030041biological_processactin filament polymerization
J0030175cellular_componentfilopodium
J0030240biological_processskeletal muscle thin filament assembly
J0031013molecular_functiontroponin I binding
J0031432molecular_functiontitin binding
J0031941cellular_componentfilamentous actin
J0032036molecular_functionmyosin heavy chain binding
J0032432cellular_componentactin filament bundle
J0042802molecular_functionidentical protein binding
J0044297cellular_componentcell body
J0048306molecular_functioncalcium-dependent protein binding
J0048741biological_processskeletal muscle fiber development
J0051017biological_processactin filament bundle assembly
J0090131biological_processmesenchyme migration
J0098723cellular_componentskeletal muscle myofibril
J0140660molecular_functioncytoskeletal motor activator activity
K0000166molecular_functionnucleotide binding
K0000287molecular_functionmagnesium ion binding
K0001725cellular_componentstress fiber
K0003785molecular_functionactin monomer binding
K0005509molecular_functioncalcium ion binding
K0005515molecular_functionprotein binding
K0005523molecular_functiontropomyosin binding
K0005524molecular_functionATP binding
K0005737cellular_componentcytoplasm
K0005856cellular_componentcytoskeleton
K0005865cellular_componentstriated muscle thin filament
K0005884cellular_componentactin filament
K0010628biological_processpositive regulation of gene expression
K0016787molecular_functionhydrolase activity
K0019904molecular_functionprotein domain specific binding
K0030027cellular_componentlamellipodium
K0030041biological_processactin filament polymerization
K0030175cellular_componentfilopodium
K0030240biological_processskeletal muscle thin filament assembly
K0031013molecular_functiontroponin I binding
K0031432molecular_functiontitin binding
K0031941cellular_componentfilamentous actin
K0032036molecular_functionmyosin heavy chain binding
K0032432cellular_componentactin filament bundle
K0042802molecular_functionidentical protein binding
K0044297cellular_componentcell body
K0048306molecular_functioncalcium-dependent protein binding
K0048741biological_processskeletal muscle fiber development
K0051017biological_processactin filament bundle assembly
K0090131biological_processmesenchyme migration
K0098723cellular_componentskeletal muscle myofibril
K0140660molecular_functioncytoskeletal motor activator activity
L0000166molecular_functionnucleotide binding
L0000287molecular_functionmagnesium ion binding
L0001725cellular_componentstress fiber
L0003785molecular_functionactin monomer binding
L0005509molecular_functioncalcium ion binding
L0005515molecular_functionprotein binding
L0005523molecular_functiontropomyosin binding
L0005524molecular_functionATP binding
L0005737cellular_componentcytoplasm
L0005856cellular_componentcytoskeleton
L0005865cellular_componentstriated muscle thin filament
L0005884cellular_componentactin filament
L0010628biological_processpositive regulation of gene expression
L0016787molecular_functionhydrolase activity
L0019904molecular_functionprotein domain specific binding
L0030027cellular_componentlamellipodium
L0030041biological_processactin filament polymerization
L0030175cellular_componentfilopodium
L0030240biological_processskeletal muscle thin filament assembly
L0031013molecular_functiontroponin I binding
L0031432molecular_functiontitin binding
L0031941cellular_componentfilamentous actin
L0032036molecular_functionmyosin heavy chain binding
L0032432cellular_componentactin filament bundle
L0042802molecular_functionidentical protein binding
L0044297cellular_componentcell body
L0048306molecular_functioncalcium-dependent protein binding
L0048741biological_processskeletal muscle fiber development
L0051017biological_processactin filament bundle assembly
L0090131biological_processmesenchyme migration
L0098723cellular_componentskeletal muscle myofibril
L0140660molecular_functioncytoskeletal motor activator activity
M0000166molecular_functionnucleotide binding
M0000287molecular_functionmagnesium ion binding
M0001725cellular_componentstress fiber
M0003785molecular_functionactin monomer binding
M0005509molecular_functioncalcium ion binding
M0005515molecular_functionprotein binding
M0005523molecular_functiontropomyosin binding
M0005524molecular_functionATP binding
M0005737cellular_componentcytoplasm
M0005856cellular_componentcytoskeleton
M0005865cellular_componentstriated muscle thin filament
M0005884cellular_componentactin filament
M0010628biological_processpositive regulation of gene expression
M0016787molecular_functionhydrolase activity
M0019904molecular_functionprotein domain specific binding
M0030027cellular_componentlamellipodium
M0030041biological_processactin filament polymerization
M0030175cellular_componentfilopodium
M0030240biological_processskeletal muscle thin filament assembly
M0031013molecular_functiontroponin I binding
M0031432molecular_functiontitin binding
M0031941cellular_componentfilamentous actin
M0032036molecular_functionmyosin heavy chain binding
M0032432cellular_componentactin filament bundle
M0042802molecular_functionidentical protein binding
M0044297cellular_componentcell body
M0048306molecular_functioncalcium-dependent protein binding
M0048741biological_processskeletal muscle fiber development
M0051017biological_processactin filament bundle assembly
M0090131biological_processmesenchyme migration
M0098723cellular_componentskeletal muscle myofibril
M0140660molecular_functioncytoskeletal motor activator activity
N0000166molecular_functionnucleotide binding
N0000287molecular_functionmagnesium ion binding
N0001725cellular_componentstress fiber
N0003785molecular_functionactin monomer binding
N0005509molecular_functioncalcium ion binding
N0005515molecular_functionprotein binding
N0005523molecular_functiontropomyosin binding
N0005524molecular_functionATP binding
N0005737cellular_componentcytoplasm
N0005856cellular_componentcytoskeleton
N0005865cellular_componentstriated muscle thin filament
N0005884cellular_componentactin filament
N0010628biological_processpositive regulation of gene expression
N0016787molecular_functionhydrolase activity
N0019904molecular_functionprotein domain specific binding
N0030027cellular_componentlamellipodium
N0030041biological_processactin filament polymerization
N0030175cellular_componentfilopodium
N0030240biological_processskeletal muscle thin filament assembly
N0031013molecular_functiontroponin I binding
N0031432molecular_functiontitin binding
N0031941cellular_componentfilamentous actin
N0032036molecular_functionmyosin heavy chain binding
N0032432cellular_componentactin filament bundle
N0042802molecular_functionidentical protein binding
N0044297cellular_componentcell body
N0048306molecular_functioncalcium-dependent protein binding
N0048741biological_processskeletal muscle fiber development
N0051017biological_processactin filament bundle assembly
N0090131biological_processmesenchyme migration
N0098723cellular_componentskeletal muscle myofibril
N0140660molecular_functioncytoskeletal motor activator activity
Functional Information from PROSITE/UniProt
site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
ATYR53-GLY63

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WITKqEYDE
ChainResidueDetails
ATRP356-GLU364

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR
ChainResidueDetails
ALEU104-ARG116

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsMOD_RES: N-acetylcysteine; in intermediate form => ECO:0000250|UniProtKB:P62737
ChainResidueDetails
ACYS0
JCYS0
KCYS0
LCYS0
MCYS0
NCYS0
BCYS0
CCYS0
DCYS0
ECYS0
FCYS0
GCYS0
HCYS0
ICYS0

site_idSWS_FT_FI2
Number of Residues14
DetailsMOD_RES: N-acetylaspartate; in Actin, alpha skeletal muscle => ECO:0000269|PubMed:1150665
ChainResidueDetails
AASP1
JASP1
KASP1
LASP1
MASP1
NASP1
BASP1
CASP1
DASP1
EASP1
FASP1
GASP1
HASP1
IASP1

site_idSWS_FT_FI3
Number of Residues28
DetailsMOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134
ChainResidueDetails
AMET44
EMET47
FMET44
FMET47
GMET44
GMET47
HMET44
HMET47
IMET44
IMET47
JMET44
AMET47
JMET47
KMET44
KMET47
LMET44
LMET47
MMET44
MMET47
NMET44
NMET47
BMET44
BMET47
CMET44
CMET47
DMET44
DMET47
EMET44

site_idSWS_FT_FI4
Number of Residues14
DetailsMOD_RES: N6-malonyllysine => ECO:0000250
ChainResidueDetails
ALYS61
JLYS61
KLYS61
LLYS61
MLYS61
NLYS61
BLYS61
CLYS61
DLYS61
ELYS61
FLYS61
GLYS61
HLYS61
ILYS61

site_idSWS_FT_FI5
Number of Residues14
DetailsMOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:1150665, ECO:0000269|PubMed:16905096, ECO:0000269|PubMed:213279, ECO:0000269|PubMed:2395459, ECO:0000269|PubMed:499690, ECO:0007744|PDB:1ATN, ECO:0007744|PDB:1NWK
ChainResidueDetails
AHIS73
JHIS73
KHIS73
LHIS73
MHIS73
NHIS73
BHIS73
CHIS73
DHIS73
EHIS73
FHIS73
GHIS73
HHIS73
IHIS73

site_idSWS_FT_FI6
Number of Residues14
DetailsMOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133
ChainResidueDetails
ALYS84
JLYS84
KLYS84
LLYS84
MLYS84
NLYS84
BLYS84
CLYS84
DLYS84
ELYS84
FLYS84
GLYS84
HLYS84
ILYS84

site_idSWS_FT_FI7
Number of Residues14
DetailsMOD_RES: ADP-ribosylarginine; by SpvB => ECO:0000305|PubMed:16905096
ChainResidueDetails
AARG177
JARG177
KARG177
LARG177
MARG177
NARG177
BARG177
CARG177
DARG177
EARG177
FARG177
GARG177
HARG177
IARG177

218853

PDB entries from 2024-04-24

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