3B4T

Crystal structure of Mycobacterium tuberculosis RNase PH, the Mycobacterium tuberculosis Structural Genomics Consortium target Rv1340

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000175	molecular_function	3'-5'-RNA exonuclease activity
A	0003723	molecular_function	RNA binding
A	0005886	cellular_component	plasma membrane
A	0006364	biological_process	rRNA processing
A	0008033	biological_process	tRNA processing
A	0009022	molecular_function	tRNA nucleotidyltransferase activity
A	0016075	biological_process	rRNA catabolic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0031125	biological_process	rRNA 3'-end processing
B	0000049	molecular_function	tRNA binding
B	0000175	molecular_function	3'-5'-RNA exonuclease activity
B	0003723	molecular_function	RNA binding
B	0005886	cellular_component	plasma membrane
B	0006364	biological_process	rRNA processing
B	0008033	biological_process	tRNA processing
B	0009022	molecular_function	tRNA nucleotidyltransferase activity
B	0016075	biological_process	rRNA catabolic process
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0031125	biological_process	rRNA 3'-end processing
C	0000049	molecular_function	tRNA binding
C	0000175	molecular_function	3'-5'-RNA exonuclease activity
C	0003723	molecular_function	RNA binding
C	0005886	cellular_component	plasma membrane
C	0006364	biological_process	rRNA processing
C	0008033	biological_process	tRNA processing
C	0009022	molecular_function	tRNA nucleotidyltransferase activity
C	0016075	biological_process	rRNA catabolic process
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0031125	biological_process	rRNA 3'-end processing
D	0000049	molecular_function	tRNA binding
D	0000175	molecular_function	3'-5'-RNA exonuclease activity
D	0003723	molecular_function	RNA binding
D	0005886	cellular_component	plasma membrane
D	0006364	biological_process	rRNA processing
D	0008033	biological_process	tRNA processing
D	0009022	molecular_function	tRNA nucleotidyltransferase activity
D	0016075	biological_process	rRNA catabolic process
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0031125	biological_process	rRNA 3'-end processing
E	0000049	molecular_function	tRNA binding
E	0000175	molecular_function	3'-5'-RNA exonuclease activity
E	0003723	molecular_function	RNA binding
E	0005886	cellular_component	plasma membrane
E	0006364	biological_process	rRNA processing
E	0008033	biological_process	tRNA processing
E	0009022	molecular_function	tRNA nucleotidyltransferase activity
E	0016075	biological_process	rRNA catabolic process
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0031125	biological_process	rRNA 3'-end processing
F	0000049	molecular_function	tRNA binding
F	0000175	molecular_function	3'-5'-RNA exonuclease activity
F	0003723	molecular_function	RNA binding
F	0005886	cellular_component	plasma membrane
F	0006364	biological_process	rRNA processing
F	0008033	biological_process	tRNA processing
F	0009022	molecular_function	tRNA nucleotidyltransferase activity
F	0016075	biological_process	rRNA catabolic process
F	0016740	molecular_function	transferase activity
F	0016779	molecular_function	nucleotidyltransferase activity
F	0031125	biological_process	rRNA 3'-end processing

Functional Information from PROSITE/UniProt

site_id	PS01277
Number of Residues	14
Details	RIBONUCLEASE_PH Ribonuclease PH signature. CDVLQADGGtrtAA

Chain	Residue	Details
A	CYS117-ALA130

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00564

Chain	Residue	Details
A	ARG87
B	ARG87
C	ARG87
D	ARG87
E	ARG87
F	ARG87

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00564, ECO:0000305|Ref.3

Chain	Residue	Details
A	GLY125
B	GLY125
C	GLY125
D	GLY125
E	GLY125
F	GLY125

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