Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 950 |
| Chain | Residue |
| A | HIS297 |
| A | HIS301 |
| A | GLU320 |
| A | PHE900 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 951 |
| Chain | Residue |
| A | HOH1710 |
| A | SER332 |
| A | ASP333 |
| A | GLY335 |
| A | HOH1166 |
| A | HOH1268 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A 952 |
| Chain | Residue |
| A | ASP452 |
| A | HOH1282 |
| A | HOH1817 |
| A | HOH1840 |
| A | HOH1844 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PHE A 900 |
| Chain | Residue |
| A | GLN119 |
| A | GLU121 |
| A | MET260 |
| A | ALA262 |
| A | MET263 |
| A | GLU264 |
| A | HIS297 |
| A | GLU298 |
| A | HIS301 |
| A | LYS319 |
| A | GLU320 |
| A | TYR376 |
| A | TYR381 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MLI A 980 |
| Chain | Residue |
| A | MET260 |
| A | GLY261 |
| A | LYS274 |
| A | TYR275 |
| A | ARG783 |
| A | ARG825 |
| A | HOH1764 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MLI A 982 |
| Chain | Residue |
| A | ALA531 |
| A | LEU532 |
| A | LEU542 |
| A | TRP546 |
| A | ASP566 |
| A | SER570 |
| A | HOH1630 |
| A | HOH1898 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 970 |
| Chain | Residue |
| A | ALA531 |
| A | LEU532 |
| A | TRP546 |
| A | SER563 |
| A | ASP566 |
| A | ALA567 |
| A | SER570 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 971 |
| Chain | Residue |
| A | TYR376 |
| A | LEU378 |
| A | GLU382 |
| A | HOH1705 |
| A | HOH2087 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 972 |
| Chain | Residue |
| A | ALA262 |
| A | ARG293 |
| A | HIS297 |
| A | GLU298 |
| A | TYR381 |
| A | PHE900 |
| A | HOH1377 |
| A | HOH1422 |
| A | HOH1764 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 973 |
| Chain | Residue |
| A | SER63 |
| A | TRP71 |
| A | THR72 |
| A | TRP74 |
| A | ARG669 |
| A | GLU671 |
| A | HOH1099 |
| A | HOH1723 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 974 |
| Chain | Residue |
| A | LEU61 |
| A | TRP74 |
| A | ARG669 |
| A | GLU671 |
| A | HOH1615 |
| A | HOH1768 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 975 |
| Chain | Residue |
| A | MET260 |
| A | GLY261 |
| A | LYS274 |
| A | TYR275 |
| A | ARG783 |
| A | ARG825 |
| A | HOH1764 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 976 |
| Chain | Residue |
| A | GLU292 |
| A | HIS672 |
| A | HOH1316 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 977 |
| Chain | Residue |
| A | ARG438 |
| A | SER441 |
| A | GLN442 |
| A | GLN475 |
| A | GLU477 |
| A | GLN479 |
| A | HOH2033 |
| A | HOH2071 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VIGHEYFHNW |
| Chain | Residue | Details |
| A | VAL294-TRP303 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU298 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU121 | |
| A | GLY261 | |
| A | HIS297 | |
| A | HIS301 | |
| A | GLU320 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000305 |
| Chain | Residue | Details |
| A | TYR381 | |
