3B1K

Crystal structure of Glyceraldehyde-3-Phosphate Dehydrogenase complexed with CP12 in the absence of copper from Synechococcus elongatus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0006006	biological_process	glucose metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0043891	molecular_function	glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity
A	0046872	molecular_function	metal ion binding
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
B	0000166	molecular_function	nucleotide binding
B	0006006	biological_process	glucose metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0043891	molecular_function	glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity
B	0046872	molecular_function	metal ion binding
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding
G	0000166	molecular_function	nucleotide binding
G	0006006	biological_process	glucose metabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0043891	molecular_function	glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity
G	0046872	molecular_function	metal ion binding
G	0050661	molecular_function	NADP binding
G	0051287	molecular_function	NAD binding
H	0000166	molecular_function	nucleotide binding
H	0006006	biological_process	glucose metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0043891	molecular_function	glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity
H	0046872	molecular_function	metal ion binding
H	0050661	molecular_function	NADP binding
H	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE NAD A 340

Chain	Residue
A	GLY11
A	GLY100
A	VAL101
A	PHE102
A	THR122
A	ALA123
A	CYS155
A	LEU186
A	ASN318
A	GLU319
C	TYR73
A	ARG12
H	SER194
J	GLU69
A	ILE13
A	ASN35
A	ASN36
A	THR37
A	ARG80
A	SER98
A	THR99

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site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE NAD B 340

Chain	Residue
B	GLY9
B	PHE10
B	GLY11
B	ARG12
B	ILE13
B	ASN35
B	ASN36
B	THR37
B	ASP79
B	ARG80
B	SER98
B	THR99
B	GLY100
B	THR122
B	CYS155
B	LEU186
B	ASN318
D	ASP66
D	TYR73
D	ASP75
I	GLU69

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site_id	AC3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE NAD G 340

Chain	Residue
B	SER194
G	ASN8
G	GLY9
G	PHE10
G	GLY11
G	ARG12
G	ILE13
G	ASN35
G	ASN36
G	THR37
G	ASP79
G	SER98
G	THR99
G	GLY100
G	PHE102
G	THR122
G	ALA123
G	CYS155
G	LEU186
G	ASN318
G	GLU319
I	TYR73

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site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE NAD H 340

Chain	Residue
H	GLY9
H	GLY11
H	ARG12
H	ILE13
H	ASN35
H	ASN36
H	THR37
H	ARG80
H	SER98
H	THR99
H	GLY100
H	THR122
H	ALA123
H	CYS155
H	LEU186
H	ASN318
H	GLU319
H	TYR322
J	TYR73

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Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
A	ALA153-LEU160

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