3B0P
tRNA-dihydrouridine synthase from Thermus thermophilus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002943 | biological_process | tRNA dihydrouridine synthesis |
| A | 0003723 | molecular_function | RNA binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0017150 | molecular_function | tRNA dihydrouridine synthase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0102264 | molecular_function | tRNA-dihydrouridine20 synthase activity |
| A | 0102266 | molecular_function | tRNA-dihydrouridine20a synthase activity |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0002943 | biological_process | tRNA dihydrouridine synthesis |
| B | 0003723 | molecular_function | RNA binding |
| B | 0008033 | biological_process | tRNA processing |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0017150 | molecular_function | tRNA dihydrouridine synthase activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0102264 | molecular_function | tRNA-dihydrouridine20 synthase activity |
| B | 0102266 | molecular_function | tRNA-dihydrouridine20a synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FMN A 351 |
| Chain | Residue |
| A | ALA9 |
| A | HIS164 |
| A | ASN203 |
| A | GLY204 |
| A | GLY205 |
| A | GLY225 |
| A | ARG226 |
| A | HOH357 |
| A | HOH394 |
| A | HOH396 |
| A | PRO10 |
| A | MET11 |
| A | VAL12 |
| A | ARG14 |
| A | MET36 |
| A | GLN63 |
| A | ASN90 |
| A | LYS132 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FMN B 351 |
| Chain | Residue |
| B | ALA9 |
| B | PRO10 |
| B | MET11 |
| B | VAL12 |
| B | ARG14 |
| B | MET36 |
| B | GLN63 |
| B | ASN90 |
| B | LYS132 |
| B | HIS164 |
| B | ASN203 |
| B | GLY204 |
| B | GLY205 |
| B | GLY225 |
| B | ARG226 |
| B | HOH356 |
| B | HOH374 |
| B | HOH407 |
| B | HOH520 |
Functional Information from PROSITE/UniProt
| site_id | PS01136 |
| Number of Residues | 19 |
| Details | UPF0034 Uncharacterized protein family UPF0034 signature. INLNlGCPsek.Aqeggy.GA |
| Chain | Residue | Details |
| A | ILE87-ALA105 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"22123979","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22123979","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3B0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B0U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3B0V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interacts with tRNA","evidences":[{"source":"PubMed","id":"22123979","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Site: {"description":"Interacts with tRNA; defines subfamily-specific binding signature","evidences":[{"source":"PubMed","id":"22123979","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25902496","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
