3AUR

Crystal structure of the human vitamin D receptor ligand binding domain complexed with Yne-diene type analog of active 14-epi-2beta-methyl-19-norvitamin D3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CA9 A 1

Chain	Residue
A	TYR143
A	HIS305
A	HIS397
A	LEU227
A	LEU233
A	SER237
A	ARG274
A	SER275
A	SER278
A	TRP286
A	VAL300

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:11344298, ECO:0007744|PDB:1DB1, ECO:0007744|PDB:1IE8

Chain	Residue	Details
A	TYR143
A	ARG274

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:11344298, ECO:0007744|PDB:1DB1

Chain	Residue	Details
A	SER237

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:11344298, ECO:0007744|PDB:1IE8

Chain	Residue	Details
A	SER278
A	HIS305

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:11344298

Chain	Residue	Details
A	HIS397

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