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3ATR

Geranylgeranyl Reductase (GGR) from Sulfolobus acidocaldarius co-crystallized with its ligand

Functional Information from GO Data
ChainGOidnamespacecontents
A0006650biological_processglycerophospholipid metabolic process
A0008654biological_processphospholipid biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0016628molecular_functionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
Functional Information from PDB Data
site_idAC1
Number of Residues41
DetailsBINDING SITE FOR RESIDUE FDA A 501
ChainResidue
AILE11
APRO46
ACYS47
AGLY48
AASP49
AALA50
ATHR120
ATHR121
AALA122
AALA156
ATHR157
AGLY12
AGLY158
ASER162
AALA185
APHE219
AALA267
AVAL269
AGLY287
AASP288
AGLY298
AGLY299
AGLY14
AGLY300
ALYS301
ADD9502
AHOH601
AHOH602
AHOH605
AHOH612
AHOH623
AHOH633
AHOH634
APHE15
AHOH661
AHOH695
AALA16
AASP35
ASER36
ALYS37
ALYS45

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE DD9 A 502
ChainResidue
AALA50
ASER52
AGLY91
AGLU92
ATYR215
AHIS297
AGLY299
AFDA501
APPV511

site_idAC3
Number of Residues8
DetailsBINDING SITE FOR RESIDUE PPV A 511
ChainResidue
ASER52
AHIS55
AASN294
AHIS297
ATYR340
ALYS343
ASER380
ADD9502

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:21515284, ECO:0000269|PubMed:24954619, ECO:0007744|PDB:3ATQ, ECO:0007744|PDB:4OPC
ChainResidueDetails
APHE15
AASP35
ALYS45
AALA122
AASP288
AGLY300

site_idSWS_FT_FI2
Number of Residues3
DetailsBINDING: BINDING => ECO:0000305|PubMed:24954619, ECO:0007744|PDB:4OPC
ChainResidueDetails
AHIS55
AHIS297
ATYR340

226707

PDB entries from 2024-10-30

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