3AJV
Splicing endonuclease from Aeropyrum pernix
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000213 | molecular_function | tRNA-intron endonuclease activity |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0006388 | biological_process | tRNA splicing, via endonucleolytic cleavage and ligation |
| A | 0016020 | cellular_component | membrane |
| B | 0000213 | molecular_function | tRNA-intron endonuclease activity |
| B | 0000379 | biological_process | tRNA-type intron splice site recognition and cleavage |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0006388 | biological_process | tRNA splicing, via endonucleolytic cleavage and ligation |
| B | 0008033 | biological_process | tRNA processing |
| B | 0016829 | molecular_function | lyase activity |
| C | 0000213 | molecular_function | tRNA-intron endonuclease activity |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0006388 | biological_process | tRNA splicing, via endonucleolytic cleavage and ligation |
| C | 0016020 | cellular_component | membrane |
| D | 0000213 | molecular_function | tRNA-intron endonuclease activity |
| D | 0000379 | biological_process | tRNA-type intron splice site recognition and cleavage |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0006388 | biological_process | tRNA splicing, via endonucleolytic cleavage and ligation |
| D | 0008033 | biological_process | tRNA processing |
| D | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 171 |
| Chain | Residue |
| A | SER82 |
| A | LEU83 |
| A | ASP84 |
| A | SER123 |
| A | TYR126 |
| A | HOH548 |
| D | ASP17 |
| D | HOH255 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 172 |
| Chain | Residue |
| A | LYS95 |
| A | ILE158 |
| A | TYR160 |
| A | HOH187 |
| B | HOH484 |
| A | ASP91 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 187 |
| Chain | Residue |
| B | ARG126 |
| B | ALA134 |
| B | PRO135 |
| B | PHE136 |
| B | ARG163 |
| B | HOH212 |
| B | HOH383 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 188 |
| Chain | Residue |
| B | ARG154 |
| B | HOH231 |
| B | HOH413 |
| B | HOH481 |
| B | HOH544 |
| D | GLY119 |
| D | ASP121 |
| D | HOH252 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 189 |
| Chain | Residue |
| B | TYR31 |
| B | GLU43 |
| B | LYS44 |
| B | ARG113 |
| B | PRO129 |
| B | HOH354 |
| B | HOH545 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 190 |
| Chain | Residue |
| B | PRO39 |
| B | LEU40 |
| B | HOH401 |
| C | ARG94 |
| C | GLY156 |
| C | LEU157 |
| C | ILE158 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 191 |
| Chain | Residue |
| B | SER57 |
| B | ILE59 |
| B | HOH289 |
| C | ARG154 |
| C | HOH190 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 171 |
| Chain | Residue |
| B | ASP17 |
| B | HOH248 |
| C | SER82 |
| C | LEU83 |
| C | ASP84 |
| C | SER123 |
| C | HOH211 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 187 |
| Chain | Residue |
| D | ALA134 |
| D | PRO135 |
| D | ARG163 |
| D | HOH194 |
| D | HOH360 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL D 188 |
| Chain | Residue |
| B | ARG94 |
| B | ASP121 |
| B | HOH353 |
| D | VAL150 |
| D | GLU151 |
| D | ARG154 |
| D | HOH217 |
| D | HOH452 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 189 |
| Chain | Residue |
| D | TYR31 |
| D | TYR35 |
| D | PRO45 |
| D | PRO129 |
| D | GLY130 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 190 |
| Chain | Residue |
| A | ARG154 |
| A | HOH198 |
| D | SER57 |
| D | ILE59 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01833 |
| Chain | Residue | Details |
| B | TYR125 | |
| B | ALA133 | |
| B | LYS164 | |
| D | TYR125 | |
| D | ALA133 | |
| D | LYS164 |
