3AGO
Crystal Structure of Ustilago sphaerogena Ribonuclease U2 complexed with adenosine 3'-monophosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0033899 | molecular_function | ribonuclease U2 activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 3AM A 115 |
| Chain | Residue |
| A | TYR39 |
| A | HIS101 |
| A | ASP108 |
| A | PHE110 |
| A | HOH149 |
| A | HOH159 |
| A | HOH162 |
| A | HOH189 |
| A | HIS41 |
| A | GLN42 |
| A | TYR43 |
| A | TYR44 |
| A | GLU46 |
| A | GLU49 |
| A | GLU62 |
| A | ARG85 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 116 |
| Chain | Residue |
| A | ASP29 |
| A | ALA31 |
| A | ASN32 |
| A | ASN38 |
| A | TYR39 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 117 |
| Chain | Residue |
| A | ASP45 |
| A | ILE51 |
| A | HOH141 |
| A | HOH215 |
| A | HOH216 |
| A | HOH220 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 118 |
| Chain | Residue |
| A | ARG35 |
| A | ASN38 |
| A | TYR39 |
| A | TYR71 |
| A | SER73 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"book","publicationDate":"1973","firstPage":"453","lastPage":"472","publisher":"Publ. House Slovak Acad. Sci.","address":"Bratislava","bookName":"Ribosomes and RNA metabolism","editors":["Zelinka J.","Balan J."],"authors":["Uchida T.","Sato S."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"book","publicationDate":"1973","firstPage":"453","lastPage":"472","publisher":"Publ. House Slovak Acad. Sci.","address":"Bratislava","bookName":"Ribosomes and RNA metabolism","editors":["Zelinka J.","Balan J."],"authors":["Uchida T.","Sato S."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"book","publicationDate":"1973","firstPage":"453","lastPage":"472","publisher":"Publ. House Slovak Acad. Sci.","address":"Bratislava","bookName":"Ribosomes and RNA metabolism","editors":["Zelinka J.","Balan J."],"authors":["Uchida T.","Sato S."]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20858208","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 13 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Methylation inactivates enzyme","evidences":[{"source":"PubMed","id":"7492561","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 908 |
| Chain | Residue | Details |
| A | HIS41 | proton shuttle (general acid/base) |
| A | GLU62 | proton shuttle (general acid/base) |
| A | ARG85 | electrostatic stabiliser |
| A | HIS101 | proton shuttle (general acid/base) |
