Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003707 | molecular_function | nuclear steroid receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0048384 | biological_process | retinoic acid receptor signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 754 A 1 |
| Chain | Residue |
| A | ILE273 |
| A | CYS437 |
| A | LEU441 |
| A | ALA276 |
| A | GLN280 |
| A | TRP310 |
| A | PHE318 |
| A | ARG321 |
| A | LEU331 |
| A | ALA332 |
| A | ILE350 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE REA B 1 |
| Chain | Residue |
| B | HOH40 |
| B | PHE228 |
| B | CYS235 |
| B | LEU269 |
| B | ARG276 |
| B | PHE286 |
| B | SER287 |
| B | VAL395 |
| B | LEU398 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | Region: {"description":"Required for nuclear export","evidences":[{"source":"UniProtKB","id":"P19793","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P19793","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by MAPK8 and MAPK9","evidences":[{"source":"PubMed","id":"10383391","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Motif: {"description":"UBR5-degron","evidences":[{"source":"PubMed","id":"37478846","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"3A9E","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by PKA","evidences":[{"source":"PubMed","id":"20215566","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"19850744","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Motif: {"description":"LXXLL motif 2"} |
