Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3A9E

Crystal structure of a mixed agonist-bound RAR-alpha and antagonist-bound RXR-alpha heterodimer ligand binding domains

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003707molecular_functionnuclear steroid receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0008270molecular_functionzinc ion binding
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
B0048384biological_processretinoic acid receptor signaling pathway
Functional Information from PDB Data
site_idAC1
Number of Residues11
DetailsBINDING SITE FOR RESIDUE 754 A 1
ChainResidue
AILE273
ACYS437
ALEU441
AALA276
AGLN280
ATRP310
APHE318
AARG321
ALEU331
AALA332
AILE350

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE REA B 1
ChainResidue
BHOH40
BPHE228
BCYS235
BLEU269
BARG276
BPHE286
BSER287
BVAL395
BLEU398

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphoserine; by PKA => ECO:0000269|PubMed:20215566
ChainResidueDetails
BSER219
BSER369

site_idSWS_FT_FI2
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:19850744
ChainResidueDetails
BLYS166
BLYS171
BLYS399

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine; by MAPK8 and MAPK9 => ECO:0000269|PubMed:10383391
ChainResidueDetails
ASER265

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon