3A4K
Crystal structural analysis of HindIII restriction endonuclease in complex with cognate DNA and divalent cations at 2.17 angstrom resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| A | 0009307 | biological_process | DNA restriction-modification system |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| B | 0009307 | biological_process | DNA restriction-modification system |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0004518 | molecular_function | nuclease activity |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| C | 0009307 | biological_process | DNA restriction-modification system |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0004518 | molecular_function | nuclease activity |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0009036 | molecular_function | type II site-specific deoxyribonuclease activity |
| D | 0009307 | biological_process | DNA restriction-modification system |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 301 |
| Chain | Residue |
| A | ASP93 |
| A | HOH320 |
| A | HOH386 |
| E | DA4 |
| E | HOH258 |
| F | DA1 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 302 |
| Chain | Residue |
| A | HOH570 |
| F | DA1 |
| A | ASP93 |
| A | ASP108 |
| A | ALA109 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 300 |
| Chain | Residue |
| A | GLU100 |
| A | ASN102 |
| D | ASP221 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 301 |
| Chain | Residue |
| C | ASP93 |
| C | HOH421 |
| G | DA4 |
| H | DA1 |
| H | HOH84 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 302 |
| Chain | Residue |
| C | ASP93 |
| C | ASP108 |
| C | ALA109 |
| C | HOH573 |
| H | DA1 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT C 300 |
| Chain | Residue |
| C | ASP161 |
| C | SER199 |
| C | THR202 |
| C | VAL204 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 301 |
| Chain | Residue |
| B | ASP93 |
| B | HOH333 |
| B | HOH342 |
| B | HOH378 |
| I | DA4 |
| J | DA1 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 302 |
| Chain | Residue |
| B | ASP93 |
| B | ASP108 |
| B | ALA109 |
| B | HOH494 |
| J | DA1 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 300 |
| Chain | Residue |
| B | LYS99 |
| B | GLU100 |
| B | ASN102 |
| C | ASP221 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 303 |
| Chain | Residue |
| B | ASP161 |
| B | SER199 |
| B | THR202 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 301 |
| Chain | Residue |
| D | ASP93 |
| D | HOH572 |
| K | DA4 |
| K | HOH337 |
| L | DA1 |
| L | HOH168 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN D 302 |
| Chain | Residue |
| D | ASP93 |
| D | ASP108 |
| D | ALA109 |
| D | HOH571 |
| L | DA1 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 300 |
| Chain | Residue |
| D | LYS201 |
| D | ASN209 |
| D | ASN210 |
| D | ASP214 |
| D | HOH338 |
| D | HOH376 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT D 303 |
| Chain | Residue |
| D | ASP161 |
| D | SER199 |
| D | THR202 |
| D | SER203 |
| D | ALA207 |
