32ZT

B. subtilis RNA Polymerase with SigF

Functional Information from PROSITE/UniProt

site_id	PS00715
Number of Residues	14
Details	SIGMA70_1 Sigma-70 factors family signature 1. DLFQiGcIGLLkSV

Chain	Residue	Details
F	ASP60-VAL73

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site_id	PS00716
Number of Residues	27
Details	SIGMA70_2 Sigma-70 factors family signature 2. TqsEVAerlgISqvqVsRLEkkiLkqI

Chain	Residue	Details
F	THR219-ILE245

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	13
Details	Motif: {"description":"Polymerase core binding"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	227
Details	Region: {"description":"Alpha N-terminal domain (alpha-NTD)","evidences":[{"source":"HAMAP-Rule","id":"MF_00059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"6WVJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33339820","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WVJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"33339827","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6WVJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6WVK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZCA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6ZFB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI7
Number of Residues	67
Details	Domain: {"description":"HTH HARE-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01261","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI8
Number of Residues	13
Details	Compositional bias: {"description":"Acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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