Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
A | 0016831 | molecular_function | carboxy-lyase activity |
A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
B | 0016831 | molecular_function | carboxy-lyase activity |
B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE 6AZ A 301 |
Chain | Residue |
A | ASP20 |
A | HOH402 |
A | HOH403 |
A | HOH406 |
A | HOH407 |
A | HOH408 |
A | HOH411 |
B | ASP75 |
B | ILE76 |
B | THR79 |
A | LYS42 |
A | LYS72 |
A | MET126 |
A | SER127 |
A | PRO180 |
A | GLN185 |
A | GLY202 |
A | ARG203 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 311 |
Chain | Residue |
A | ASN210 |
A | HOH522 |
A | HOH725 |
A | HOH746 |
B | THR159 |
B | PRO161 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 312 |
Chain | Residue |
A | THR159 |
A | PRO161 |
A | HOH519 |
A | HOH525 |
B | GLU33 |
B | ASN210 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE GOL A 314 |
Chain | Residue |
A | ASP209 |
A | ASN210 |
A | ALA213 |
A | ALA214 |
B | GLU162 |
site_id | AC5 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE 6AZ B 302 |
Chain | Residue |
A | ASP75 |
A | ILE76 |
A | THR79 |
A | HOH472 |
B | ASP20 |
B | LYS42 |
B | LYS72 |
B | MET126 |
B | SER127 |
B | PRO180 |
B | GLN185 |
B | GLY202 |
B | ARG203 |
B | HOH422 |
B | HOH423 |
B | HOH426 |
B | HOH427 |
B | HOH428 |
B | HOH431 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL B 313 |
Chain | Residue |
A | GLU162 |
B | ASP209 |
B | ASN210 |
B | ALA213 |
B | ALA214 |
B | HOH706 |
Functional Information from PROSITE/UniProt
site_id | PS00156 |
Number of Residues | 14 |
Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IIaDfKvaDIPeTN |
Chain | Residue | Details |
A | ILE67-ASN80 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
A | LYS72 | |
B | LYS72 | |
site_id | SWS_FT_FI2 |
Number of Residues | 14 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP20 | |
B | ASP70 | |
B | SER127 | |
B | PRO180 | |
B | GLY202 | |
B | ARG203 | |
A | LYS42 | |
A | ASP70 | |
A | SER127 | |
A | PRO180 | |
A | GLY202 | |
A | ARG203 | |
B | ASP20 | |
B | LYS42 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
A | LYS72 | |
A | ASP70 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
B | LYS72 | |
B | ASP70 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
A | LYS42 | |
A | ASP75 | |
A | LYS72 | |
A | ASP70 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
B | LYS42 | |
B | ASP75 | |
B | LYS72 | |
B | ASP70 | |