2ZY9

Improved crystal structure of magnesium transporter MgtE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005886	cellular_component	plasma membrane
A	0006812	biological_process	monoatomic cation transport
A	0008324	molecular_function	monoatomic cation transmembrane transporter activity
A	0015095	molecular_function	magnesium ion transmembrane transporter activity
A	0015693	biological_process	magnesium ion transport
A	0016020	cellular_component	membrane
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0098655	biological_process	monoatomic cation transmembrane transport
A	1903830	biological_process	magnesium ion transmembrane transport
B	0000287	molecular_function	magnesium ion binding
B	0005886	cellular_component	plasma membrane
B	0006812	biological_process	monoatomic cation transport
B	0008324	molecular_function	monoatomic cation transmembrane transporter activity
B	0015095	molecular_function	magnesium ion transmembrane transporter activity
B	0015693	biological_process	magnesium ion transport
B	0016020	cellular_component	membrane
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0098655	biological_process	monoatomic cation transmembrane transport
B	1903830	biological_process	magnesium ion transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 453

Chain	Residue
A	ASP259
A	ASP418

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 454

Chain	Residue
A	ASP91
A	ASP92
A	THR244
A	ASP247

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 455

Chain	Residue
A	ALA223
A	ASP226
B	ASP250

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 456

Chain	Residue
A	ASP95
A	GLN98
A	GLY136

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 451

Chain	Residue
B	ASP226

---

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG B 453

Chain	Residue
B	ASP259

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 454

Chain	Residue
B	ASP91
B	GLU166
B	ASP247

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 457

Chain	Residue
A	ASP246
A	ASP250
B	ALA223
B	ASP226

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG B 455

Chain	Residue
B	ASP95
B	GLY136

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	234
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U9L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4U9N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WIB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	22
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"17700703","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	46
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"17700703","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	124
Details	Domain: {"description":"CBS 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	112
Details	Domain: {"description":"CBS 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00703","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5X9G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZY9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5X9H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28747715","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZY9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25367295","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4U9N","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19798051","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---