2ZJ4

Isomerase domain of human glucose:fructose-6-phosphate amidotransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0097367	molecular_function	carbohydrate derivative binding
A	1901135	biological_process	carbohydrate derivative metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE AGP A 1

Chain	Residue
A	GLY374
A	SER473
A	LYS557
A	GLU560
A	HIS576
A	HOH685
A	HOH692
A	HOH696
A	HOH700
A	HOH702
A	HOH728
A	THR375
A	SER376
A	SER420
A	GLN421
A	SER422
A	THR425
A	VAL471
A	ALA472

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	139
Details	Domain: {"description":"SIS 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00797","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	141
Details	Domain: {"description":"SIS 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00797","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19059404","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2V4M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZJ3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZJ4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1jxa

Chain	Residue	Details
A	LYS675
A	GLU553
A	LYS557
A	GLU560

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1jxa

Chain	Residue	Details
A	HIS576

---