2Z77
X-ray crystal structure of RV0760c from Mycobacterium tuberculosis in complex with estradiol-17beta-hemisuccinate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0032934 | molecular_function | sterol binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0032934 | molecular_function | sterol binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0032934 | molecular_function | sterol binding |
| C | 0042803 | molecular_function | protein homodimerization activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0032934 | molecular_function | sterol binding |
| D | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACT B 300 |
| Chain | Residue |
| B | ASP40 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT C 400 |
| Chain | Residue |
| C | ALA70 |
| C | ARG72 |
| C | GLU98 |
| C | ASP100 |
| C | GLY101 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HE7 B 200 |
| Chain | Residue |
| B | LEU73 |
| B | LEU95 |
| B | SER97 |
| B | PHE99 |
| B | SER105 |
| B | PHE135 |
| C | THR66 |
| C | HIS67 |
| C | PHE99 |
| C | ASP100 |
| C | PHE103 |
| C | HE7200 |
| C | HOH427 |
| B | VAL46 |
| B | HIS67 |
| B | ASN71 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HE7 C 200 |
| Chain | Residue |
| B | LEU130 |
| B | HE7200 |
| C | SER16 |
| C | TRP17 |
| C | VAL20 |
| C | ASP40 |
| C | VAL46 |
| C | PHE63 |
| C | HIS67 |
| C | LEU73 |
| C | VAL75 |
| C | TYR113 |
| C | MET124 |
| C | TRP128 |
| C | MET133 |
| C | HOH476 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE HE7 A 200 |
| Chain | Residue |
| A | ASP40 |
| A | HIS67 |
| A | LEU95 |
| A | SER97 |
| A | SER105 |
| A | TRP128 |
| A | MET133 |
| C | HOH478 |
| D | SER45 |
| D | VAL46 |
| D | LEU130 |
| D | HOH213 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NCA D 200 |
| Chain | Residue |
| D | SER16 |
| D | TRP17 |
| D | TRP28 |
| D | ASP40 |
| D | LEU73 |
| D | PHE111 |
| D | TYR113 |
| D | MET124 |
