2YYY
Crystal structure of Glyceraldehyde-3-phosphate dehydrogenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| A | 0043891 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity |
| A | 0047100 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0004365 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0043891 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] (phosphorylating) activity |
| B | 0047100 | molecular_function | glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP B 1001 |
| Chain | Residue |
| B | ASN8 |
| B | ALA54 |
| B | GLY88 |
| B | ALA89 |
| B | PRO90 |
| B | ILE93 |
| B | ASN97 |
| B | GLN112 |
| B | GLY114 |
| B | CYS144 |
| B | ARG172 |
| B | GLY9 |
| B | ASP175 |
| B | GLN307 |
| B | HOH1004 |
| B | HOH1005 |
| B | HOH1062 |
| B | HOH1075 |
| B | HOH1119 |
| B | HOH1127 |
| B | HOH1142 |
| B | TYR10 |
| B | GLY11 |
| B | SER12 |
| B | ILE13 |
| B | LYS34 |
| B | THR35 |
| B | LYS36 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP A 2001 |
| Chain | Residue |
| A | ASN8 |
| A | GLY9 |
| A | TYR10 |
| A | GLY11 |
| A | SER12 |
| A | ILE13 |
| A | LYS34 |
| A | THR35 |
| A | LYS36 |
| A | ALA54 |
| A | GLY88 |
| A | ALA89 |
| A | PRO90 |
| A | ILE93 |
| A | ASN97 |
| A | GLN112 |
| A | GLY114 |
| A | CYS144 |
| A | ARG172 |
| A | ASP175 |
| A | GLN307 |
| A | HOH2025 |
| A | HOH2038 |
| A | HOH2045 |
| A | HOH2099 |
| A | HOH2100 |
| A | HOH2105 |
| A | HOH2112 |
Functional Information from PROSITE/UniProt
| site_id | PS00071 |
| Number of Residues | 8 |
| Details | GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. VSCNTTgL |
| Chain | Residue | Details |
| A | VAL142-LEU149 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS144 | |
| B | CYS144 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER12 | |
| B | ARG172 | |
| B | HIS198 | |
| B | GLN307 | |
| A | GLY114 | |
| A | SER143 | |
| A | ARG172 | |
| A | HIS198 | |
| A | GLN307 | |
| B | SER12 | |
| B | GLY114 | |
| B | SER143 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1szj |
| Chain | Residue | Details |
| A | HIS226 | |
| A | CYS144 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1szj |
| Chain | Residue | Details |
| B | HIS226 | |
| B | CYS144 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1szj |
| Chain | Residue | Details |
| A | CYS144 | |
| A | ARG171 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1szj |
| Chain | Residue | Details |
| B | CYS144 | |
| B | ARG171 |
