2YWB

Crystal structure of GMP synthetase from Thermus thermophilus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003921	molecular_function	GMP synthase activity
A	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006177	biological_process	GMP biosynthetic process
A	0006541	biological_process	glutamine metabolic process
A	0016874	molecular_function	ligase activity
A	0044281	biological_process	small molecule metabolic process
B	0000166	molecular_function	nucleotide binding
B	0003921	molecular_function	GMP synthase activity
B	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
B	0005524	molecular_function	ATP binding
B	0005829	cellular_component	cytosol
B	0006164	biological_process	purine nucleotide biosynthetic process
B	0006177	biological_process	GMP biosynthetic process
B	0006541	biological_process	glutamine metabolic process
B	0016874	molecular_function	ligase activity
B	0044281	biological_process	small molecule metabolic process
C	0000166	molecular_function	nucleotide binding
C	0003921	molecular_function	GMP synthase activity
C	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
C	0005524	molecular_function	ATP binding
C	0005829	cellular_component	cytosol
C	0006164	biological_process	purine nucleotide biosynthetic process
C	0006177	biological_process	GMP biosynthetic process
C	0006541	biological_process	glutamine metabolic process
C	0016874	molecular_function	ligase activity
C	0044281	biological_process	small molecule metabolic process
D	0000166	molecular_function	nucleotide binding
D	0003921	molecular_function	GMP synthase activity
D	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
D	0005524	molecular_function	ATP binding
D	0005829	cellular_component	cytosol
D	0006164	biological_process	purine nucleotide biosynthetic process
D	0006177	biological_process	GMP biosynthetic process
D	0006541	biological_process	glutamine metabolic process
D	0016874	molecular_function	ligase activity
D	0044281	biological_process	small molecule metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_00344

Chain	Residue	Details
A	CYS78
B	CYS78
C	CYS78
D	CYS78

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site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00344

Chain	Residue	Details
A	HIS164
A	GLU166
B	HIS164
B	GLU166
C	HIS164
C	GLU166
D	HIS164
D	GLU166

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00344

Chain	Residue	Details
A	SER217
B	SER217
C	SER217
D	SER217

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