2YRF
Crystal structure of 5-methylthioribose 1-phosphate isomerase from Bacillus subtilis complexed with sulfate ion
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| A | 0044237 | biological_process | cellular metabolic process |
| A | 0044249 | biological_process | cellular biosynthetic process |
| A | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019284 | biological_process | L-methionine salvage from S-adenosylmethionine |
| B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| B | 0044237 | biological_process | cellular metabolic process |
| B | 0044249 | biological_process | cellular biosynthetic process |
| B | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | ARG51 |
| A | GLY52 |
| A | ARG94 |
| A | CYS160 |
| A | GLN199 |
| A | LYS251 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| B | CYS160 |
| B | GLN199 |
| B | LYS251 |
| B | PHE317 |
| B | ARG51 |
| B | GLY52 |
| B | ARG94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | ASP240 | |
| B | ASP240 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ARG51 | |
| B | ARG94 | |
| B | GLN199 | |
| B | ASN250 | |
| A | ARG51 | |
| A | ARG94 | |
| A | GLN199 | |
| A | ASN250 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer |
| Chain | Residue | Details |
| A | CYS160 | |
| B | CYS160 |
