2YPP
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051260 | biological_process | protein homooligomerization |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051260 | biological_process | protein homooligomerization |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 700 |
| Chain | Residue |
| A | CYS87 |
| A | HIS369 |
| A | GLU411 |
| A | ASP441 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TYR A 800 |
| Chain | Residue |
| A | HOH2054 |
| A | HOH2077 |
| B | TYR173 |
| B | ALA174 |
| A | PHE91 |
| A | ARG171 |
| A | ALA174 |
| A | ASN175 |
| A | HOH2028 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 900 |
| Chain | Residue |
| A | GLY282 |
| A | GLU283 |
| A | LYS306 |
| A | ARG337 |
| A | HIS369 |
| A | HOH2063 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 901 |
| Chain | Residue |
| A | ARG135 |
| A | SER136 |
| A | ALA137 |
| A | ARG284 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 902 |
| Chain | Residue |
| A | GLN70 |
| A | VAL121 |
| A | VAL122 |
| A | GLU242 |
| A | HOH2037 |
| A | HOH2038 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 903 |
| Chain | Residue |
| A | SER62 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 904 |
| Chain | Residue |
| A | ALA35 |
| A | GLN36 |
| B | SER136 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 905 |
| Chain | Residue |
| A | GLU63 |
| A | MET180 |
| A | THR187 |
| A | ILE243 |
| A | HIS277 |
| A | HOH2015 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 700 |
| Chain | Residue |
| B | CYS87 |
| B | HIS369 |
| B | GLU411 |
| B | ASP441 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TYR B 800 |
| Chain | Residue |
| A | TYR173 |
| A | ALA174 |
| A | HOH2001 |
| A | HOH2055 |
| B | PHE91 |
| B | ARG171 |
| B | ALA174 |
| B | ASN175 |
| B | HOH2024 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TYR B 801 |
| Chain | Residue |
| B | LEU15 |
| B | PRO16 |
| B | LEU18 |
| B | ARG23 |
| B | LEU26 |
| B | GLU53 |
| B | ARG256 |
| B | HOH2053 |
| B | HOH2054 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 900 |
| Chain | Residue |
| B | GLY282 |
| B | GLU283 |
| B | LYS306 |
| B | ARG337 |
| B | HIS369 |
| B | HOH2057 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 901 |
| Chain | Residue |
| B | LEU18 |
| B | ARG23 |
| B | HOH2001 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 902 |
| Chain | Residue |
| B | GLN70 |
| B | VAL121 |
| B | GLN239 |
| B | GLU242 |
| B | HOH2012 |
| B | HOH2030 |
| B | HOH2031 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 903 |
| Chain | Residue |
| B | ARG135 |
| B | SER136 |
| B | ALA137 |
| B | ARG284 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 904 |
| Chain | Residue |
| B | ARG66 |
| B | THR187 |
| B | GLU242 |
| B | ILE243 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 905 |
| Chain | Residue |
| B | SER62 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16288916, ECO:0007744|PDB:2B7O |
| Chain | Residue | Details |
| A | CYS87 | |
| B | ARG126 | |
| B | GLU283 | |
| B | LYS306 | |
| B | ARG337 | |
| B | HIS369 | |
| B | GLU411 | |
| B | ASP441 | |
| A | ARG126 | |
| A | GLU283 | |
| A | LYS306 | |
| A | ARG337 | |
| A | HIS369 | |
| A | GLU411 | |
| A | ASP441 | |
| B | CYS87 |
