2YOB
High resolution AGXT_M structure
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004760 | molecular_function | serine-pyruvate transaminase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005777 | cellular_component | peroxisome |
A | 0005782 | cellular_component | peroxisomal matrix |
A | 0005829 | cellular_component | cytosol |
A | 0006563 | biological_process | L-serine metabolic process |
A | 0007219 | biological_process | Notch signaling pathway |
A | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
A | 0008483 | molecular_function | transaminase activity |
A | 0009436 | biological_process | glyoxylate catabolic process |
A | 0016597 | molecular_function | amino acid binding |
A | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
A | 0019448 | biological_process | L-cysteine catabolic process |
A | 0030170 | molecular_function | pyridoxal phosphate binding |
A | 0042802 | molecular_function | identical protein binding |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0042853 | biological_process | L-alanine catabolic process |
A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
A | 0046487 | biological_process | glyoxylate metabolic process |
A | 0046724 | biological_process | oxalic acid secretion |
B | 0004760 | molecular_function | serine-pyruvate transaminase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005777 | cellular_component | peroxisome |
B | 0005782 | cellular_component | peroxisomal matrix |
B | 0005829 | cellular_component | cytosol |
B | 0006563 | biological_process | L-serine metabolic process |
B | 0007219 | biological_process | Notch signaling pathway |
B | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
B | 0008483 | molecular_function | transaminase activity |
B | 0009436 | biological_process | glyoxylate catabolic process |
B | 0016597 | molecular_function | amino acid binding |
B | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
B | 0019448 | biological_process | L-cysteine catabolic process |
B | 0030170 | molecular_function | pyridoxal phosphate binding |
B | 0042802 | molecular_function | identical protein binding |
B | 0042803 | molecular_function | protein homodimerization activity |
B | 0042853 | biological_process | L-alanine catabolic process |
B | 0043231 | cellular_component | intracellular membrane-bounded organelle |
B | 0046487 | biological_process | glyoxylate metabolic process |
B | 0046724 | biological_process | oxalic acid secretion |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE PLP A 1389 |
Chain | Residue |
A | SER81 |
A | GLN208 |
A | LYS209 |
B | TYR260 |
B | THR263 |
A | GLY82 |
A | HIS83 |
A | TRP108 |
A | GLY156 |
A | SER158 |
A | ASP183 |
A | VAL185 |
A | ALA186 |
site_id | AC2 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE PLP B 1389 |
Chain | Residue |
A | TYR260 |
A | THR263 |
B | SER81 |
B | GLY82 |
B | HIS83 |
B | TRP108 |
B | GLY156 |
B | SER158 |
B | ASP183 |
B | VAL185 |
B | ALA186 |
B | GLN208 |
B | LYS209 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 1390 |
Chain | Residue |
B | ARG258 |
B | HOH2009 |
B | HOH2073 |
B | HOH2231 |
B | HOH2303 |
B | HOH2304 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE BTB A 1390 |
Chain | Residue |
A | TRP246 |
A | ASN249 |
A | ASP254 |
A | MET259 |
A | HOH2288 |
A | HOH2290 |
site_id | AC5 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE BTB B 1391 |
Chain | Residue |
A | HOH2193 |
B | LYS245 |
B | TRP246 |
B | ASN249 |
B | ASP254 |
B | GLN256 |
B | MET259 |
B | GOL1393 |
B | HOH2221 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 1391 |
Chain | Residue |
A | LYS5 |
B | ARG197 |
B | HIS342 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL A 1392 |
Chain | Residue |
A | ASN72 |
A | SER223 |
A | ASP224 |
A | HOH2145 |
A | HOH2260 |
A | HOH2272 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 1393 |
Chain | Residue |
A | SER50 |
A | LYS51 |
A | HOH2109 |
A | HOH2111 |
A | HOH2389 |
A | HOH2390 |
B | GLN23 |
B | MET340 |
site_id | AC9 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 1394 |
Chain | Residue |
A | MET38 |
A | ALA39 |
A | GLY42 |
A | HOH2092 |
A | HOH2096 |
A | HOH2392 |
B | GLY42 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE GOL B 1392 |
Chain | Residue |
B | THR135 |
B | LEU136 |
B | HOH2148 |
B | HOH2307 |
site_id | BC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL A 1395 |
Chain | Residue |
A | VAL336 |
A | SER337 |
A | MET340 |
A | HOH2347 |
A | HOH2352 |
A | HOH2356 |
A | HOH2365 |
A | HOH2393 |
site_id | BC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL B 1393 |
Chain | Residue |
A | HOH2182 |
A | HOH2193 |
B | LYS236 |
B | TRP246 |
B | BTB1391 |
B | HOH2220 |
Functional Information from PROSITE/UniProt
site_id | PS00595 |
Number of Residues | 21 |
Details | AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. IDILysGSQKalnappGtSlI |
Chain | Residue | Details |
A | ILE200-ILE220 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | BINDING: |
Chain | Residue | Details |
A | ARG360 | |
B | ARG360 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569 |
Chain | Residue | Details |
A | THR9 | |
B | THR9 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | MOD_RES: N6-(pyridoxal phosphate)lysine |
Chain | Residue | Details |
A | LYS209 | |
B | LYS209 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:O35423 |
Chain | Residue | Details |
A | LYS225 | |
B | LYS225 |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O35423 |
Chain | Residue | Details |
A | LYS234 | |
A | LYS312 | |
B | LYS234 | |
B | LYS312 |