2YOB
High resolution AGXT_M structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004760 | molecular_function | L-serine-pyruvate transaminase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005777 | cellular_component | peroxisome |
| A | 0005782 | cellular_component | peroxisomal matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0006563 | biological_process | L-serine metabolic process |
| A | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0009436 | biological_process | glyoxylate catabolic process |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
| A | 0019448 | biological_process | L-cysteine catabolic process |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0042853 | biological_process | L-alanine catabolic process |
| A | 0046487 | biological_process | glyoxylate metabolic process |
| B | 0004760 | molecular_function | L-serine-pyruvate transaminase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005777 | cellular_component | peroxisome |
| B | 0005782 | cellular_component | peroxisomal matrix |
| B | 0005829 | cellular_component | cytosol |
| B | 0006563 | biological_process | L-serine metabolic process |
| B | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0009436 | biological_process | glyoxylate catabolic process |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
| B | 0019448 | biological_process | L-cysteine catabolic process |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0042853 | biological_process | L-alanine catabolic process |
| B | 0046487 | biological_process | glyoxylate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP A 1389 |
| Chain | Residue |
| A | SER81 |
| A | GLN208 |
| A | LYS209 |
| B | TYR260 |
| B | THR263 |
| A | GLY82 |
| A | HIS83 |
| A | TRP108 |
| A | GLY156 |
| A | SER158 |
| A | ASP183 |
| A | VAL185 |
| A | ALA186 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PLP B 1389 |
| Chain | Residue |
| A | TYR260 |
| A | THR263 |
| B | SER81 |
| B | GLY82 |
| B | HIS83 |
| B | TRP108 |
| B | GLY156 |
| B | SER158 |
| B | ASP183 |
| B | VAL185 |
| B | ALA186 |
| B | GLN208 |
| B | LYS209 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1390 |
| Chain | Residue |
| B | ARG258 |
| B | HOH2009 |
| B | HOH2073 |
| B | HOH2231 |
| B | HOH2303 |
| B | HOH2304 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BTB A 1390 |
| Chain | Residue |
| A | TRP246 |
| A | ASN249 |
| A | ASP254 |
| A | MET259 |
| A | HOH2288 |
| A | HOH2290 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BTB B 1391 |
| Chain | Residue |
| A | HOH2193 |
| B | LYS245 |
| B | TRP246 |
| B | ASN249 |
| B | ASP254 |
| B | GLN256 |
| B | MET259 |
| B | GOL1393 |
| B | HOH2221 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1391 |
| Chain | Residue |
| A | LYS5 |
| B | ARG197 |
| B | HIS342 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1392 |
| Chain | Residue |
| A | ASN72 |
| A | SER223 |
| A | ASP224 |
| A | HOH2145 |
| A | HOH2260 |
| A | HOH2272 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1393 |
| Chain | Residue |
| A | SER50 |
| A | LYS51 |
| A | HOH2109 |
| A | HOH2111 |
| A | HOH2389 |
| A | HOH2390 |
| B | GLN23 |
| B | MET340 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1394 |
| Chain | Residue |
| A | MET38 |
| A | ALA39 |
| A | GLY42 |
| A | HOH2092 |
| A | HOH2096 |
| A | HOH2392 |
| B | GLY42 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 1392 |
| Chain | Residue |
| B | THR135 |
| B | LEU136 |
| B | HOH2148 |
| B | HOH2307 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1395 |
| Chain | Residue |
| A | VAL336 |
| A | SER337 |
| A | MET340 |
| A | HOH2347 |
| A | HOH2352 |
| A | HOH2356 |
| A | HOH2365 |
| A | HOH2393 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 1393 |
| Chain | Residue |
| A | HOH2182 |
| A | HOH2193 |
| B | LYS236 |
| B | TRP246 |
| B | BTB1391 |
| B | HOH2220 |
Functional Information from PROSITE/UniProt
| site_id | PS00595 |
| Number of Residues | 21 |
| Details | AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. IDILysGSQKalnappGtSlI |
| Chain | Residue | Details |
| A | ILE200-ILE220 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"O35423","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"O35423","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
