2YFR

Crystal structure of inulosucrase from Lactobacillus johnsonii NCC533

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009758	biological_process	carbohydrate utilization
A	0050053	molecular_function	levansucrase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1709

Chain	Residue
A	ASP419
A	GLN450
A	TRP487
A	ASN489
A	ASP521
A	HOH2276

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 1710

Chain	Residue
A	GLN338
A	TYR355
A	LYS357

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT A 1711

Chain	Residue
A	LYS250
A	ASN320
A	SO41721
A	HOH2497

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 1712

Chain	Residue
A	ASP500
A	ASN503
A	HOH2336

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT A 1713

Chain	Residue
A	ARG545

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1714

Chain	Residue
A	GLU625
A	LYS629
A	GLY630
A	HIS632
A	HOH2088
A	HOH2498

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1715

Chain	Residue
A	LYS264
A	LYS264
A	VAL265
A	HOH2079
A	HOH2499
A	HOH2501

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 1716

Chain	Residue
A	ASN364
A	HIS390
A	ASP392
A	LYS678
A	PRO687
A	GLY688
A	HOH2240
A	HOH2502
A	HOH2503

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1717

Chain	Residue
A	TYR376
A	ASP392
A	ASN393
A	LYS502
A	HOH2470

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1718

Chain	Residue
A	ASP318
A	ASN320
A	HIS321

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1719

Chain	Residue
A	LYS248
A	ASN669
A	ASP671
A	SO41721
A	HOH2504

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1720

Chain	Residue
A	SER211
A	LYS212
A	GLU213

---

site_id	BC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 A 1721

Chain	Residue
A	SER247
A	LYS248
A	GLU380
A	ASP382
A	ACT1711
A	SO41719
A	HOH2051
A	HOH2505
A	HOH2506
A	HOH2507

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1722

Chain	Residue
A	ARG238
A	ARG238
A	HOH2508

---

site_id	BC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 1723

Chain	Residue
A	ASP272
A	TRP339
A	SER340
A	ARG424
A	ASP425
A	GLU441
A	GLU524
A	GOL1730
A	GOL1731

---

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1724

Chain	Residue
A	ASP480
A	ARG484
A	MET553
A	ASN556
A	LYS557
A	ASP695
A	LEU698

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1725

Chain	Residue
A	ARG610
A	LYS654
A	TRP663
A	HOH2447
A	HOH2509

---

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1726

Chain	Residue
A	ASP431
A	ASP432
A	TYR535
A	LEU573
A	HOH2510

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1727

Chain	Residue
A	ASP318
A	ASN657
A	HOH2511
A	HOH2512

---

site_id	CC2
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GOL A 1728

Chain	Residue
A	ALA558
A	VAL559
A	GLY560
A	PRO592
A	VAL694
A	LEU698
A	ILE699
A	GLY700
A	GLY701
A	TYR702
A	ASN703
A	LEU704
A	ASN556
A	LYS557

---

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1729

Chain	Residue
A	LYS534
A	VAL569
A	SER570
A	ASP571
A	ASN647
A	HOH2513
A	HOH2514

---

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1730

Chain	Residue
A	TRP271
A	MET296
A	ASN305
A	ARG623
A	GOL1723

---

site_id	CC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 1731

Chain	Residue
A	ASP272
A	GLU524
A	ARG542
A	TYR600
A	SER601
A	TYR619
A	ARG623
A	GOL1723

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000303|PubMed:21801732

Chain	Residue	Details
A	ASP272

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000303|PubMed:21801732

Chain	Residue	Details
A	GLU524

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:21801732

Chain	Residue	Details
A	TRP271
A	SER340
A	ARG424
A	GLU522
A	ARG542

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:21801732, ECO:0007744|PDB:2YFS

Chain	Residue	Details
A	ASN317
A	ASP660
A	ILE662
A	SER667

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:21801732, ECO:0007744|PDB:2YFR, ECO:0007744|PDB:2YFS, ECO:0007744|PDB:2YFT

Chain	Residue	Details
A	ASP419
A	GLN450
A	TRP487
A	ASN489
A	ASP521

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	SITE: Transition state stabilizer => ECO:0000303|PubMed:21801732

Chain	Residue	Details
A	ASP425

---