Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2YFH

Structure of a Chimeric Glutamate Dehydrogenase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
A	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
A	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
A	0005829	cellular_component	cytosol
A	0006520	biological_process	amino acid metabolic process
A	0006537	biological_process	glutamate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
A	0019552	biological_process	L-glutamate catabolic process via 2-hydroxyglutarate
A	0055114	biological_process	obsolete oxidation-reduction process
B	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
B	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
B	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
B	0005829	cellular_component	cytosol
B	0006520	biological_process	amino acid metabolic process
B	0006537	biological_process	glutamate biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
B	0019552	biological_process	L-glutamate catabolic process via 2-hydroxyglutarate
B	0055114	biological_process	obsolete oxidation-reduction process
C	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
C	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
C	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
C	0005829	cellular_component	cytosol
C	0006520	biological_process	amino acid metabolic process
C	0006537	biological_process	glutamate biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
C	0019552	biological_process	L-glutamate catabolic process via 2-hydroxyglutarate
C	0055114	biological_process	obsolete oxidation-reduction process
D	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
D	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
D	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
D	0005829	cellular_component	cytosol
D	0006520	biological_process	amino acid metabolic process
D	0006537	biological_process	glutamate biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
D	0019552	biological_process	L-glutamate catabolic process via 2-hydroxyglutarate
D	0055114	biological_process	obsolete oxidation-reduction process
E	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
E	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
E	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
E	0005829	cellular_component	cytosol
E	0006520	biological_process	amino acid metabolic process
E	0006537	biological_process	glutamate biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
E	0019552	biological_process	L-glutamate catabolic process via 2-hydroxyglutarate
E	0055114	biological_process	obsolete oxidation-reduction process
F	0004352	molecular_function	glutamate dehydrogenase (NAD+) activity
F	0004353	molecular_function	glutamate dehydrogenase [NAD(P)+] activity
F	0004354	molecular_function	glutamate dehydrogenase (NADP+) activity
F	0005829	cellular_component	cytosol
F	0006520	biological_process	amino acid metabolic process
F	0006537	biological_process	glutamate biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0016639	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor
F	0019552	biological_process	L-glutamate catabolic process via 2-hydroxyglutarate
F	0055114	biological_process	obsolete oxidation-reduction process

Functional Information from PROSITE/UniProt

site_id	PS00074
Number of Residues	14
Details	GLFV_DEHYDROGENASE Glu / Leu / Phe / Val dehydrogenases active site. LpmGGAKgGsdfDP

Chain	Residue	Details
A	LEU120-PRO133

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10011","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details