Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004035 | molecular_function | alkaline phosphatase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0004035 | molecular_function | alkaline phosphatase activity |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 1524 |
| Chain | Residue |
| A | CYS124 |
| A | ASP151 |
| A | TYR154 |
| A | HIS382 |
| A | PO41527 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1525 |
| Chain | Residue |
| A | PO41527 |
| A | HOH2095 |
| A | ASP151 |
| A | ASP209 |
| A | ASP210 |
| A | ASP380 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1526 |
| Chain | Residue |
| A | ASP210 |
| A | ASN215 |
| A | ASN216 |
| A | PO41527 |
| A | HOH2227 |
| A | HOH2303 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1527 |
| Chain | Residue |
| A | CYS124 |
| A | ASP151 |
| A | TYR154 |
| A | ASP210 |
| A | HIS211 |
| A | ASP380 |
| A | HIS382 |
| A | ARG506 |
| A | HIS510 |
| A | FE1524 |
| A | CA1525 |
| A | CA1526 |
| A | HOH2227 |
| A | HOH2303 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PE5 A 529 |
| Chain | Residue |
| A | GLY319 |
| A | SER368 |
| A | LYS369 |
| A | HOH2304 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PE5 A 530 |
| Chain | Residue |
| A | ALA197 |
| A | HOH2305 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PE5 A 531 |
| Chain | Residue |
| A | TYR347 |
| A | ASP353 |
| A | ARG359 |
| A | HOH2306 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 532 |
| Chain | Residue |
| A | PRO158 |
| A | HIS171 |
| A | ASN172 |
| A | EDO550 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PE5 A 534 |
| Chain | Residue |
| A | ARG444 |
| A | THR446 |
| A | GLN451 |
| A | LYS453 |
| A | ASP455 |
| A | SER474 |
| A | VAL487 |
| A | SER488 |
| A | HOH2307 |
| B | THR491 |
| B | GLN493 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 535 |
| Chain | Residue |
| A | ASP17 |
| A | PRO18 |
| A | LEU19 |
| A | ARG249 |
| A | ARG263 |
| A | HIS264 |
| A | PHE265 |
| A | HOH2308 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PE5 A 536 |
| Chain | Residue |
| A | HOH2309 |
| B | ASN302 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 537 |
| Chain | Residue |
| A | LYS142 |
| A | ASP144 |
| A | EDO561 |
| A | HOH2092 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 539 |
| Chain | Residue |
| A | ASP283 |
| A | ASP284 |
| A | ARG303 |
| A | HOH2310 |
| B | GLY225 |
| B | GLN226 |
| B | SER227 |
| B | VAL228 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 540 |
| Chain | Residue |
| A | PHE339 |
| A | GLU503 |
| A | GLU504 |
| A | HOH2311 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 541 |
| Chain | Residue |
| A | ASP418 |
| A | TYR439 |
| A | THR491 |
| A | ILE492 |
| A | GLY495 |
| A | LYS497 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 545 |
| Chain | Residue |
| A | THR178 |
| A | ASP181 |
| A | EDO550 |
| A | EDO565 |
| A | HOH2313 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PE5 A 546 |
| Chain | Residue |
| A | HIS55 |
| A | ARG91 |
| A | VAL101 |
| A | HOH2055 |
| A | HOH2062 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 548 |
| Chain | Residue |
| A | LEU233 |
| A | ARG234 |
| A | HOH2142 |
| A | HOH2314 |
| A | HOH2315 |
| A | ILE177 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 549 |
| Chain | Residue |
| A | GLU65 |
| A | MET66 |
| A | LYS68 |
| A | SER74 |
| A | VAL75 |
| A | HIS76 |
| A | HOH2316 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 550 |
| Chain | Residue |
| A | SER173 |
| A | ALA174 |
| A | ASP181 |
| A | EDO532 |
| A | EDO545 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 551 |
| Chain | Residue |
| A | GLU394 |
| A | GLU429 |
| A | EDO579 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 552 |
| Chain | Residue |
| A | TYR161 |
| A | HIS382 |
| A | SER509 |
| A | HOH2317 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PE5 A 553 |
| Chain | Residue |
| A | SER251 |
| A | TYR262 |
| A | ARG263 |
| A | HOH2147 |
| A | HOH2155 |
| A | HOH2156 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PE5 A 554 |
| Chain | Residue |
| A | LYS224 |
| A | ASN288 |
| A | HOH2177 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PE5 A 555 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PE5 A 557 |
| Chain | Residue |
| A | PRO2 |
| A | ASN3 |
| A | PHE4 |
| A | SER5 |
| A | PRO31 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PE5 A 558 |
| Chain | Residue |
| A | ASN3 |
| A | HIS96 |
| A | ASN167 |
| site_id | DC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 561 |
| Chain | Residue |
| A | LYS103 |
| A | THR104 |
| A | LYS105 |
| A | LEU143 |
| A | ALA201 |
| A | PHE202 |
| A | PRO203 |
| A | EDO537 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 562 |
| Chain | Residue |
| A | LEU71 |
| A | PRO254 |
| A | EDO564 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 564 |
| Chain | Residue |
| A | GLN240 |
| A | GLY256 |
| A | EDO562 |
| A | HOH2318 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 565 |
| Chain | Residue |
| A | ASP181 |
| A | ASN184 |
| A | EDO545 |
| A | HOH2106 |
| A | HOH2319 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 566 |
| Chain | Residue |
| A | LYS486 |
| A | SER489 |
| A | HOH2320 |
| B | PE5538 |
| site_id | DC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 569 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 576 |
| Chain | Residue |
| A | HIS264 |
| A | THR266 |
| A | SER272 |
| A | SER320 |
| A | HOH2324 |
| site_id | DC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 577 |
| Chain | Residue |
| A | ASP284 |
| A | GLN285 |
| A | HOH2129 |
| A | HOH2134 |
| A | HOH2174 |
| A | HOH2177 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 579 |
| Chain | Residue |
| A | LYS336 |
| A | PHE393 |
| A | THR396 |
| A | PRO431 |
| A | HIS432 |
| A | EDO551 |
| site_id | EC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PE5 A 575 |
| Chain | Residue |
| A | LYS220 |
| A | VAL228 |
| A | HOH2131 |
| B | ASN219 |
| B | LYS220 |
| B | HOH2133 |
| site_id | EC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PE5 A 580 |
| site_id | EC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PE5 A 581 |
| Chain | Residue |
| A | TYR89 |
| A | LYS103 |
| A | HOH2065 |
| A | HOH2087 |
| A | HOH2325 |
| site_id | EC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 582 |
| Chain | Residue |
| A | GLU175 |
| A | GLU214 |
| A | GLN517 |
| A | HOH2096 |
| A | HOH2138 |
| A | HOH2139 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 1585 |
| Chain | Residue |
| A | ASN300 |
| A | ASN302 |
| B | SER227 |
| B | PE5536 |
| site_id | EC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE B 1524 |
| Chain | Residue |
| B | CYS124 |
| B | ASP151 |
| B | TYR154 |
| B | HIS382 |
| B | PO41527 |
| site_id | EC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 1525 |
| Chain | Residue |
| B | ASP151 |
| B | ASP209 |
| B | ASP210 |
| B | ASP380 |
| B | PO41527 |
| B | HOH2092 |
| site_id | EC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 1526 |
| Chain | Residue |
| B | ASP210 |
| B | HIS211 |
| B | ASN215 |
| B | ASN216 |
| B | PO41527 |
| B | HOH2216 |
| B | HOH2285 |
| site_id | EC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1527 |
| Chain | Residue |
| B | CYS124 |
| B | ASP151 |
| B | TYR154 |
| B | ASP210 |
| B | HIS211 |
| B | ASP380 |
| B | HIS382 |
| B | ARG506 |
| B | HIS510 |
| B | FE1524 |
| B | CA1525 |
| B | CA1526 |
| B | HOH2216 |
| B | HOH2285 |
| site_id | FC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PE5 B 529 |
| Chain | Residue |
| B | GLY319 |
| B | SER368 |
| B | LYS369 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PE5 B 530 |
| Chain | Residue |
| B | VAL101 |
| B | ALA197 |
| B | PE5581 |
| B | HOH2086 |
| site_id | FC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PE5 B 531 |
| Chain | Residue |
| B | TYR347 |
| B | ASP353 |
| B | PRO356 |
| B | ARG359 |
| B | HOH2286 |
| site_id | FC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 532 |
| Chain | Residue |
| B | HIS171 |
| B | ASN172 |
| site_id | FC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PE5 B 534 |
| Chain | Residue |
| A | THR491 |
| A | GLN493 |
| B | ARG444 |
| B | THR446 |
| B | GLN451 |
| B | LYS453 |
| B | ASP455 |
| B | VAL487 |
| B | HOH2244 |
| site_id | FC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 535 |
| Chain | Residue |
| B | ASP17 |
| B | ARG249 |
| B | HOH2287 |
| B | HOH2288 |
| site_id | FC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PE5 B 536 |
| Chain | Residue |
| A | ASN302 |
| A | NA1585 |
| B | ALA230 |
| B | HOH2289 |
| site_id | FC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 537 |
| Chain | Residue |
| B | LYS142 |
| B | LEU143 |
| B | ASP144 |
| site_id | FC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 540 |
| Chain | Residue |
| B | ASN291 |
| B | PHE339 |
| B | GLU503 |
| B | GLU504 |
| B | HOH2290 |
| site_id | GC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 541 |
| Chain | Residue |
| B | ASP418 |
| B | TYR439 |
| B | THR491 |
| B | ILE492 |
| B | GLY495 |
| B | LYS497 |
| B | HOH2108 |
| site_id | GC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 545 |
| Chain | Residue |
| B | THR178 |
| B | ASP181 |
| B | EDO565 |
| B | HOH2291 |
| site_id | GC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PE5 B 546 |
| Chain | Residue |
| B | GLU54 |
| B | HIS55 |
| B | ARG91 |
| B | VAL101 |
| B | HOH2054 |
| B | HOH2292 |
| site_id | GC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 548 |
| Chain | Residue |
| B | ILE177 |
| B | LEU233 |
| B | ARG234 |
| B | HOH2145 |
| B | HOH2294 |
| B | HOH2295 |
| site_id | GC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 549 |
| Chain | Residue |
| B | GLU65 |
| B | MET66 |
| B | LYS68 |
| B | VAL75 |
| B | HIS76 |
| B | HOH2296 |
| site_id | GC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 550 |
| Chain | Residue |
| B | SER173 |
| B | ALA174 |
| B | ASP181 |
| B | HOH2291 |
| site_id | GC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 551 |
| Chain | Residue |
| B | SER342 |
| B | GLU429 |
| B | EDO579 |
| site_id | GC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 552 |
| Chain | Residue |
| B | TYR161 |
| B | HIS382 |
| B | GLY413 |
| B | GLU501 |
| B | HOH2297 |
| site_id | GC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PE5 B 553 |
| Chain | Residue |
| B | TYR262 |
| B | HOH2150 |
| site_id | HC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PE5 B 554 |
| Chain | Residue |
| B | LYS224 |
| B | ASN288 |
| B | HOH2178 |
| site_id | HC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PE5 B 555 |
| site_id | HC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PE5 B 557 |
| Chain | Residue |
| B | PRO2 |
| B | ASN3 |
| B | PHE4 |
| B | SER5 |
| B | PRO31 |
| B | PRO40 |
| site_id | HC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PE5 B 558 |
| Chain | Residue |
| B | ALA1 |
| B | ASN3 |
| B | HIS96 |
| site_id | HC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 560 |
| Chain | Residue |
| B | ILE433 |
| B | GLN434 |
| site_id | HC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 561 |
| Chain | Residue |
| B | LYS103 |
| B | THR104 |
| B | LYS105 |
| B | LEU143 |
| B | ALA201 |
| B | PRO203 |
| site_id | HC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 562 |
| site_id | HC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 565 |
| Chain | Residue |
| B | ASP181 |
| B | ASN184 |
| B | EDO545 |
| B | HOH2110 |
| site_id | HC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 566 |
| Chain | Residue |
| B | LYS486 |
| B | PE5538 |
| site_id | IC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 569 |
| Chain | Residue |
| B | ASP192 |
| B | ALA193 |
| B | HOH2114 |
| B | HOH2298 |
| site_id | IC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 573 |
| site_id | IC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 576 |
| Chain | Residue |
| B | HIS264 |
| B | THR266 |
| B | SER272 |
| B | ASN317 |
| B | SER320 |
| B | SER321 |
| B | HOH2300 |
| site_id | IC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 577 |
| Chain | Residue |
| B | ASP284 |
| B | GLN285 |
| B | HOH2130 |
| B | HOH2136 |
| B | HOH2176 |
| B | HOH2178 |
| site_id | IC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 579 |
| Chain | Residue |
| B | LYS336 |
| B | PHE393 |
| B | THR396 |
| B | PRO431 |
| B | HIS432 |
| B | EDO551 |
| site_id | IC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PE5 B 580 |
| Chain | Residue |
| B | LYS68 |
| B | SER70 |
| B | LEU71 |
| site_id | IC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PE5 B 581 |
| Chain | Residue |
| B | TYR89 |
| B | LYS103 |
| B | ALA201 |
| B | PE5530 |
| B | HOH2085 |
| B | HOH2088 |
| site_id | IC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 582 |
| Chain | Residue |
| B | GLU175 |
| B | GLU214 |
| B | GLN517 |
| B | HOH2093 |
| B | HOH2138 |
| B | HOH2141 |
| site_id | IC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 1585 |
| Chain | Residue |
| A | GLN226 |
| A | SER227 |
| B | ASN300 |
| B | ASN302 |
| site_id | JC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PE5 B 538 |
| Chain | Residue |
| A | LYS486 |
| A | SER489 |
| A | EDO566 |
| B | ARG472 |
| B | VAL487 |
| B | SER488 |
| B | SER489 |
| B | THR491 |
| B | EDO566 |
| site_id | JC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PE5 B 556 |
| Chain | Residue |
| B | VAL60 |
| B | LYS62 |
| B | HOH2028 |
| site_id | JC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PE5 B 568 |
| Chain | Residue |
| A | LYS52 |
| A | LYS86 |
| B | GLU83 |
| B | LYS86 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
