2YEM
Crystal Structure of the Second Bromodomain of Human Brd4 with the inhibitor GW841819X
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE WSH A 1459 |
| Chain | Residue |
| A | PRO375 |
| A | ARG413 |
| A | ASN433 |
| A | VAL439 |
| A | HOH2034 |
| A | HOH2067 |
| B | WSH1460 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE WSH B 1460 |
| Chain | Residue |
| B | TRP374 |
| B | PRO375 |
| B | LEU387 |
| B | ASN433 |
| B | HIS437 |
| B | GLU438 |
| B | VAL439 |
| B | HOH2021 |
| A | TRP374 |
| A | WSH1459 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Site: {"description":"Acetylated histone binding","evidences":[{"source":"PubMed","id":"22464331","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
