2Y8U

A. nidulans chitin deacetylase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000272	biological_process	polysaccharide catabolic process
A	0004099	molecular_function	chitin deacetylase activity
A	0005575	cellular_component	cellular_component
A	0005576	cellular_component	extracellular region
A	0005975	biological_process	carbohydrate metabolic process
A	0006032	biological_process	chitin catabolic process
A	0008061	molecular_function	chitin binding
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0046872	molecular_function	metal ion binding
A	0071555	biological_process	cell wall organization
B	0000272	biological_process	polysaccharide catabolic process
B	0004099	molecular_function	chitin deacetylase activity
B	0005575	cellular_component	cellular_component
B	0005576	cellular_component	extracellular region
B	0005975	biological_process	carbohydrate metabolic process
B	0006032	biological_process	chitin catabolic process
B	0008061	molecular_function	chitin binding
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0046872	molecular_function	metal ion binding
B	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 A 1238

Chain	Residue
A	ASP47
A	ASP48
A	HIS97
A	HIS101
A	TYR138
A	HIS196
A	CO1239
A	HOH2007
A	HOH2061

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 1239

Chain	Residue
A	ASP48
A	HIS97
A	HIS101
A	PO41238
A	HOH2007

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA A 1240

Chain	Residue
A	GLY189

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 1241

Chain	Residue
A	THR34
A	NA1244
A	HOH2003

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 1242

Chain	Residue
A	PHE179

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 1244

Chain	Residue
A	THR34
A	PRO125
A	NA1241

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B 1238

Chain	Residue
B	ASP47
B	ASP48
B	HIS97
B	HIS101
B	TYR138
B	HIS196
B	CO1239
B	HOH2057

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CO B 1239

Chain	Residue
B	ASP48
B	HIS97
B	HIS101
B	PO41238

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 1240

Chain	Residue
B	ARG118
B	HOH2029

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU01014

Chain	Residue	Details
A	ASP47
B	ASP47

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU01014

Chain	Residue	Details
A	HIS196
B	HIS196

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q6DWK3

Chain	Residue	Details
A	ASP47
A	TYR138
B	ASP47
B	TYR138

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01014

Chain	Residue	Details
A	ASP48
A	HIS97
A	HIS101
B	ASP48
B	HIS97
B	HIS101

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	SITE: May prevent de-N-acetylated sugar residues from interacting with the active site => ECO:0000303|PubMed:28496100

Chain	Residue	Details
A	LYS164
B	LYS164

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498

Chain	Residue	Details
A	ASN176
B	ASN176

---