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2Y5G

FACTOR XA - CATION INHIBITOR COMPLEX

Functional Information from GO Data
ChainGOidnamespacecontents
A0004252molecular_functionserine-type endopeptidase activity
A0006508biological_processproteolysis
Functional Information from PDB Data
site_idAC1
Number of Residues18
DetailsBINDING SITE FOR RESIDUE FJD A 1244
ChainResidue
AGLN61
AVAL213
ATRP215
AGLY216
AGLY218
AGLY226
AILE227
ATYR228
AHOH2248
AHOH2279
AGLU97
ATHR98
ATYR99
APHE174
AASP189
AALA190
AGLN192
ASER195

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 1245
ChainResidue
AASP70
AASN72
AGLN75
AGLU80
AHOH2064
AHOH2065

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 1246
ChainResidue
ATYR185
AASP185
AARG222
ALYS224
AHOH2225
AHOH2257

Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC
ChainResidueDetails
ALEU53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPHV
ChainResidueDetails
AASP189-VAL200

site_idPS01186
Number of Residues16
DetailsEGF_2 EGF-like domain signature 2. CsCarGYtladngkaC
ChainResidueDetails
LCYS109-CYS124

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Charge relay system
ChainResidueDetails
AHIS57
AASP102
ASER195

227344

PDB entries from 2024-11-13

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