2Y1N
Structure of c-Cbl-ZAP-70 peptide complex
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0001784 | molecular_function | phosphotyrosine residue binding |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0007166 | biological_process | cell surface receptor signaling pathway |
| A | 0023051 | biological_process | regulation of signaling |
| A | 0046872 | molecular_function | metal ion binding |
| C | 0001784 | molecular_function | phosphotyrosine residue binding |
| C | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0007166 | biological_process | cell surface receptor signaling pathway |
| C | 0023051 | biological_process | regulation of signaling |
| C | 0046872 | molecular_function | metal ion binding |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1436 |
| 鎖名 | 残基 |
| A | CYS381 |
| A | CYS384 |
| A | CYS401 |
| A | CYS404 |
| site_id | AC2 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1437 |
| 鎖名 | 残基 |
| A | CYS396 |
| A | HIS398 |
| A | CYS416 |
| A | CYS419 |
| site_id | AC3 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN C 1436 |
| 鎖名 | 残基 |
| C | CYS384 |
| C | CYS401 |
| C | CYS404 |
| C | CYS381 |
| site_id | AC4 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN C 1437 |
| 鎖名 | 残基 |
| C | CYS396 |
| C | HIS398 |
| C | CYS416 |
| C | CYS419 |
| site_id | AC5 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE CA A 1438 |
| 鎖名 | 残基 |
| A | ASP229 |
| A | THR231 |
| A | ASN233 |
| A | TYR235 |
| A | GLU240 |
| A | HOH2071 |
| site_id | AC6 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE CA C 1438 |
| 鎖名 | 残基 |
| C | ASP229 |
| C | THR231 |
| C | ASN233 |
| C | TYR235 |
| C | GLU240 |
| C | HOH2080 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 2 |
| 詳細 | MOD_RES: Phosphoserine => ECO:0007744|PubMed:15144186 |
| 鎖名 | 残基 | 詳細 |
| B | SER4 | |
| D | SER4 |
| site_id | SWS_FT_FI2 |
| 残基数 | 2 |
| 詳細 | MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:8943331, ECO:0007744|PubMed:19690332 |
| 鎖名 | 残基 | 詳細 |
| B | PTR7 | |
| C | GLU240 | |
| D | PTR7 | |
| A | ASN233 | |
| A | TYR235 | |
| A | GLU240 | |
| C | ASP229 | |
| C | THR231 | |
| C | ASN233 | |
| C | TYR235 |
| site_id | SWS_FT_FI3 |
| 残基数 | 2 |
| 詳細 | BINDING: BINDING => ECO:0000250 |
| 鎖名 | 残基 | 詳細 |
| A | ARG294 | |
| C | ARG294 |
| site_id | SWS_FT_FI4 |
| 残基数 | 2 |
| 詳細 | MOD_RES: Phosphotyrosine; by INSR => ECO:0000269|PubMed:11997497 |
| 鎖名 | 残基 | 詳細 |
| A | TYR371 | |
| C | TYR371 |
