2XZP

Upf1 helicase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE GOL A 1915

Chain	Residue
A	ARG422

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL A 1916

Chain	Residue
A	GOL1917
A	LEU509
A	GLY513
A	ASN514
A	GLY515
A	PRO516
A	VAL517
A	ARG631
A	SER632

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 1917

Chain	Residue
A	ASN514
A	GLY515
A	GOL1916

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MLI A 1918

Chain	Residue
A	PRO493
A	PRO494
A	GLY495
A	THR496
A	GLN665
A	ARG703
A	GLY831
A	ARG865

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MLI A 1919

Chain	Residue
A	GLY495
A	VAL500

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	228
Details	Domain: {"description":"UPF1-type SF1B helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU01433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	212
Details	Domain: {"description":"UPF1-type SF1B helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU01433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17159905","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17159905","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2GK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17159905","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21419344","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2GJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XZO","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---