2XZL

Upf1-RNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1851

Chain	Residue
A	CYS62
A	CYS65
A	CYS84
A	HIS94

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1852

Chain	Residue
A	CYS76
A	CYS79
A	HIS98
A	HIS104

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1853

Chain	Residue
A	CYS125
A	CYS148
A	CYS152
A	CYS122

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE ADP A 1854

Chain	Residue
A	GLN408
A	GLN413
A	GLY433
A	THR434
A	GLY435
A	LYS436
A	THR437
A	VAL438
A	TYR638
A	ARG639
A	GLU769
A	ALF1855
A	MG1856
A	HOH2090
A	HOH2091

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ALF A 1855

Chain	Residue
A	PRO432
A	GLY433
A	LYS436
A	GLN601
A	ARG639
A	GLY767
A	ARG801
A	ADP1854
A	MG1856
A	HOH2047
A	HOH2051

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 1856

Chain	Residue
A	THR437
A	ADP1854
A	ALF1855
A	HOH2038
A	HOH2047
A	HOH2090

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 1PE A 1857

Chain	Residue
A	GLY377
A	TYR381
A	ARG678

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 1PE A 1858

Chain	Residue
A	GLY720
A	LYS722
A	GLN725
A	ASP771
A	TYR804

---

site_id	AC9
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 1PE A 1859

Chain	Residue
A	ALA369
A	ILE370
A	SER671
A	LYS672
A	PHE673
A	TRP675
A	PRO676
A	ILE677
A	ARG678
A	1PE1863

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 1PE A 1860

Chain	Residue
A	PHE647
A	ASN650
A	MET651
A	HIS823
A	HIS827

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE 1PE A 1861

Chain	Residue
A	GLN362
A	ASN841
A	GLN843

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE 1PE A 1862

Chain	Residue
A	ARG829
A	LEU834
A	LEU844
A	CYS845
A	VAL847
A	LEU849
A	HOH2086

---

site_id	BC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 1PE A 1863

Chain	Residue
A	ASN641
A	ILE663
A	THR667
A	TRP675
A	ILE677
A	GLY679
A	ILE680
A	PRO681
A	1PE1859

---

site_id	BC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 1PE A 1864

Chain	Residue
A	HIS419
A	ARG423
A	LEU425
A	SER426
A	LEU427
A	HIS629
A	VAL630
A	PRO631
A	ILE632

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 1PE A 1865

Chain	Residue
A	GLN592
A	PHE393
A	HIS451
A	ASP453
A	LYS591

---

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 1PE A 1866

Chain	Residue
A	SER412
A	ASN415
A	ALA416
A	ILE632
A	ARG633

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 1PE A 1867

Chain	Residue
A	LYS367
A	ASP371
A	LYS373
A	THR564
A	LYS588

---

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 1PE A 1868

Chain	Residue
A	LYS372
A	ILE375
A	SER376
A	GLY589

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Region: {"description":"C3H","evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	28
Details	Region: {"description":"CC/SHH/C","evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01341","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q92900","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---