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2XWP

ANAEROBIC COBALT CHELATASE (CbiK) FROM SALMONELLA TYPHIMURIUM IN COMPLEX WITH METALATED TETRAPYRROLE

Functional Information from GO Data
ChainGOidnamespacecontents
A0006779biological_processporphyrin-containing compound biosynthetic process
A0009236biological_processcobalamin biosynthetic process
A0016829molecular_functionlyase activity
A0016852molecular_functionsirohydrochlorin cobaltochelatase activity
A0019251biological_processanaerobic cobalamin biosynthetic process
A0046872molecular_functionmetal ion binding
A0046906molecular_functiontetrapyrrole binding
A0050897molecular_functioncobalt ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues29
DetailsBINDING SITE FOR RESIDUE SIR A 1259
ChainResidue
APHE10
AILE84
AILE85
AGLY87
AASP88
AGLU89
ALYS92
AHIS145
AGLY146
AALA147
AMET201
ATHR43
ALEU202
AVAL203
AHIS207
AALA208
AHOH2061
AHOH2139
AHOH2140
AHOH2141
AHOH2142
AHOH2143
ASER44
AGLY45
AMET46
AALA71
AGLN72
AGLY73
AHIS83

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL A 1260
ChainResidue
AARG52
ALYS68
AGLN72
AHOH2144
AHOH2145

Functional Information from PROSITE/UniProt
site_idPS00761
Number of Residues14
DetailsSPASE_I_3 Signal peptidases I signature 3. MLVAGDHAinDmaS
ChainResidueDetails
AMET201-SER214

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000305|PubMed:21173279
ChainResidueDetails
AHIS145

site_idSWS_FT_FI2
Number of Residues9
DetailsBINDING: BINDING => ECO:0000269|PubMed:21173279, ECO:0007744|PDB:2XWP
ChainResidueDetails
AGLY45
AILE84
AILE85
AASP88
AGLU89
ALYS92
ALEU202
AVAL203
AHIS207

site_idSWS_FT_FI3
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q72EC8
ChainResidueDetails
AHIS145
AGLU175

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PDB entries from 2024-10-30

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