2XWP

ANAEROBIC COBALT CHELATASE (CbiK) FROM SALMONELLA TYPHIMURIUM IN COMPLEX WITH METALATED TETRAPYRROLE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006779	biological_process	porphyrin-containing compound biosynthetic process
A	0009236	biological_process	cobalamin biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016852	molecular_function	sirohydrochlorin cobaltochelatase activity
A	0019251	biological_process	anaerobic cobalamin biosynthetic process
A	0046872	molecular_function	metal ion binding
A	0046906	molecular_function	tetrapyrrole binding
A	0050897	molecular_function	cobalt ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	29
Details	BINDING SITE FOR RESIDUE SIR A 1259

Chain	Residue
A	PHE10
A	ILE84
A	ILE85
A	GLY87
A	ASP88
A	GLU89
A	LYS92
A	HIS145
A	GLY146
A	ALA147
A	MET201
A	THR43
A	LEU202
A	VAL203
A	HIS207
A	ALA208
A	HOH2061
A	HOH2139
A	HOH2140
A	HOH2141
A	HOH2142
A	HOH2143
A	SER44
A	GLY45
A	MET46
A	ALA71
A	GLN72
A	GLY73
A	HIS83

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1260

Chain	Residue
A	ARG52
A	LYS68
A	GLN72
A	HOH2144
A	HOH2145

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Functional Information from PROSITE/UniProt

site_id	PS00761
Number of Residues	14
Details	SPASE_I_3 Signal peptidases I signature 3. MLVAGDHAinDmaS

Chain	Residue	Details
A	MET201-SER214

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21173279","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21173279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XWP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q72EC8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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