2XVZ

Cobalt chelatase CbiK (periplasmatic) from Desulvobrio vulgaris Hildenborough (co-crystallized with cobalt)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016829	molecular_function	lyase activity
A	0016852	molecular_function	sirohydrochlorin cobaltochelatase activity
A	0019251	biological_process	anaerobic cobalamin biosynthetic process
A	0020037	molecular_function	heme binding
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
A	0050897	molecular_function	cobalt ion binding
A	0051262	biological_process	protein tetramerization
A	0051266	molecular_function	sirohydrochlorin ferrochelatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE HEM A 1270

Chain	Residue
A	PRO91
A	HIS96
A	HIS96
A	LEU99
A	LEU99
A	LEU119
A	PRO159
A	HOH2040
A	HOH2105

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CO A 1271

Chain	Residue
A	HIS154
A	GLU184
A	HIS216
A	PER1285
A	HOH2106

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1272

Chain	Residue
A	GLY92
A	GLU93
A	GLU94
A	THR156
A	HIS158
A	HOH2037
A	HOH2055
A	HOH2107

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1273

Chain	Residue
A	PHE17
A	LEU87
A	HIS88
A	THR89
A	MET210
A	ALA211
A	NA1283
A	HOH2108

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1274

Chain	Residue
A	ARG114
A	VAL115
A	SER116
A	VAL117
A	ARG267

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1275

Chain	Residue
A	LEU174
A	ASP175
A	ASP197
A	ARG236
A	HOH2065

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 1276

Chain	Residue
A	TRP172
A	PRO176
A	ARG199

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1277

Chain	Residue
A	THR49
A	LYS51
A	MET52
A	GLU94

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1278

Chain	Residue
A	PRO140
A	ALA141
A	HOH2109

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 1279

Chain	Residue
A	SER250
A	ASP251
A	ALA252

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1280

Chain	Residue
A	THR19
A	SER20
A	VAL21
A	ASP215
A	SO41281
A	HOH2110

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 1281

Chain	Residue
A	GLY214
A	ASP215
A	HIS216
A	SO41280
A	HOH2106
A	HOH2110
A	HOH2111

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1282

Chain	Residue
A	PRO43
A	VAL44
A	ARG45
A	HOH2112

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA A 1283

Chain	Residue
A	GLY153
A	HIS154
A	TYR164
A	SO41273

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PER A 1285

Chain	Residue
A	HIS154
A	GLU184
A	HIS216
A	CO1271

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"21173279","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"21173279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XVX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XVZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"21173279","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XVZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---