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2XV4

Structure of Human RPC62 (partial)

Functional Information from GO Data
ChainGOidnamespacecontents
S0000428cellular_componentDNA-directed RNA polymerase complex
S0003677molecular_functionDNA binding
S0003697molecular_functionsingle-stranded DNA binding
S0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
S0005515molecular_functionprotein binding
S0005634cellular_componentnucleus
S0005654cellular_componentnucleoplasm
S0005666cellular_componentRNA polymerase III complex
S0005829cellular_componentcytosol
S0006351biological_processDNA-templated transcription
S0006359biological_processregulation of transcription by RNA polymerase III
S0032728biological_processpositive regulation of interferon-beta production
S0045087biological_processinnate immune response
S0045089biological_processpositive regulation of innate immune response
S0051607biological_processdefense response to virus
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PO4 S 1533
ChainResidue
SHIS16
SMET85
SLEU112

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE PO4 S 1534
ChainResidue
SHOH2019
SLEU12
SGLU15
SHIS16
SILE447
SARG450
SGLU513

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE PO4 S 1535
ChainResidue
SARG87
SHIS243
SPHE521
SGLU524
SSER525
SGLU528

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
SSER194

226707

PDB entries from 2024-10-30

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