2XS4
Structure of karilysin catalytic MMP domain in complex with magnesium
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 997 |
| Chain | Residue |
| A | SER75 |
| A | SER78 |
| A | HOH2070 |
| A | HOH2072 |
| A | HOH2192 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 998 |
| Chain | Residue |
| A | HIS102 |
| A | ASP104 |
| A | HIS117 |
| A | HIS133 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 999 |
| Chain | Residue |
| A | HIS155 |
| A | HIS159 |
| A | HIS165 |
| B | ALA301 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 1202 |
| Chain | Residue |
| A | ASN87 |
| A | ASN143 |
| A | GLY144 |
| A | SER145 |
| A | HOH2132 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VAAHEIGHLL |
| Chain | Residue | Details |
| A | VAL152-LEU161 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10095","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21166898","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23695557","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21166898","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23695557","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
