2XQC

DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE AND ZN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0004803	molecular_function	transposase activity
A	0006310	biological_process	DNA recombination
A	0006313	biological_process	DNA transposition
A	0016787	molecular_function	hydrolase activity
A	0032196	biological_process	transposition
A	0046872	molecular_function	metal ion binding
D	0003677	molecular_function	DNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0004803	molecular_function	transposase activity
D	0006310	biological_process	DNA recombination
D	0006313	biological_process	DNA transposition
D	0016787	molecular_function	hydrolase activity
D	0032196	biological_process	transposition
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 1138

Chain	Residue
A	HIS67
A	HIS69
C	DT5
C	DG6
D	HIS137

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 1139

Chain	Residue
A	HOH2136
B	DC31
A	PRO114
A	HOH2133
A	HOH2134
A	HOH2135

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1140

Chain	Residue
A	ASP45
A	ASP49
D	GLU134
D	ASP138

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN B 1038

Chain	Residue
B	HOH2057
B	HOH2058
B	HOH2059
B	HOH2060
B	HOH2061
B	HOH2062

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN C 1007

Chain	Residue
C	DG3
C	HOH2019
C	HOH2020
C	HOH2021
C	HOH2022
C	HOH2023

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 1141

Chain	Residue
A	HIS137
D	HIS67
D	HIS69
F	DT5
F	DG6

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN D 1142

Chain	Residue
D	ASP45
D	HOH2125
D	HOH2126
D	HOH2127
D	HOH2128
D	HOH2129

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN E 1038

Chain	Residue
D	PRO114
E	DC31
E	HOH2095
E	HOH2096
E	HOH2097
E	HOH2098

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN E 1039

Chain	Residue
E	HOH2099
E	HOH2100
E	HOH2101
E	HOH2102
E	HOH2103
E	HOH2104

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Region: {"description":"Mobile alpha helix","evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Site: {"description":"Critical for recognizing and stabilizing G:T mismatch in DNA substrate","evidences":[{"source":"PubMed","id":"20890269","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---