2XQ2
Structure of the K294A mutant of vSGLT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005412 | molecular_function | D-glucose:sodium symporter activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006814 | biological_process | sodium ion transport |
| A | 0008645 | biological_process | hexose transmembrane transport |
| A | 0015293 | molecular_function | symporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0034219 | biological_process | carbohydrate transmembrane transport |
| A | 0035725 | biological_process | sodium ion transmembrane transport |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005412 | molecular_function | D-glucose:sodium symporter activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0006814 | biological_process | sodium ion transport |
| B | 0008645 | biological_process | hexose transmembrane transport |
| B | 0015293 | molecular_function | symporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0034219 | biological_process | carbohydrate transmembrane transport |
| B | 0035725 | biological_process | sodium ion transmembrane transport |
| B | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1574 |
| Chain | Residue |
| A | PHE194 |
| A | SER569 |
| A | ILE572 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 1575 |
| Chain | Residue |
| A | GLU233 |
| A | ILE235 |
| A | TYR539 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG A 1576 |
| Chain | Residue |
| A | ALA62 |
Functional Information from PROSITE/UniProt
| site_id | PS00312 |
| Number of Residues | 10 |
| Details | GLYCOPHORIN_A Glycophorin A signature. IIfGVMAGVI |
| Chain | Residue | Details |
| A | ILE553-ILE562 | |
| B | ILE553-ILE562 |
| site_id | PS00456 |
| Number of Residues | 26 |
| Details | NA_SOLUT_SYMP_1 Sodium:solute symporter family signature 1. GipLmysILGLALFalvYSiyGGLsA |
| Chain | Residue | Details |
| A | GLY159-ALA184 | |
| B | GLY159-ALA184 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 240 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| B | SER79-GLY99 | |
| B | GLY455-LEU475 | |
| B | MET483-ILE503 | |
| B | SER523-TRP543 | |
| A | MET483-ILE503 | |
| A | SER523-TRP543 | |
| B | ILE129-LEU149 | |
| B | THR156-TYR176 | |
| B | VAL193-GLY213 | |
| B | LEU246-PHE266 | |
| B | ILE287-ALA307 | |
| B | PHE345-SER365 | |
| B | THR401-GLY421 | |
| B | ILE427-PHE447 |
