2XNJ
Crystal structure of an engineered Ferredoxin(flavodoxin) NADP(H) Reductase (FPR) from Escherichia coli
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FAD A 1257 |
| Chain | Residue |
| A | PHE36 |
| A | TYR72 |
| A | GLY82 |
| A | LYS83 |
| A | LEU84 |
| A | SER85 |
| A | THR125 |
| A | HIS255 |
| A | TYR256 |
| A | NAP1258 |
| A | HOH2048 |
| A | ARG50 |
| A | HOH2102 |
| A | HOH2187 |
| A | HOH2188 |
| A | HOH2190 |
| A | HOH2191 |
| A | HOH2192 |
| A | ALA51 |
| A | TYR52 |
| A | SER53 |
| A | TYR66 |
| A | LEU67 |
| A | VAL68 |
| A | VAL70 |
| site_id | AC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAP A 1258 |
| Chain | Residue |
| A | ASP17 |
| A | ALA18 |
| A | VAL68 |
| A | THR69 |
| A | VAL70 |
| A | VAL71 |
| A | THR123 |
| A | ALA152 |
| A | ARG153 |
| A | SER182 |
| A | ARG183 |
| A | ARG193 |
| A | PRO195 |
| A | ASN223 |
| A | GLN225 |
| A | MET226 |
| A | ASP229 |
| A | FAD1257 |
| A | TRS1259 |
| A | HOH2113 |
| A | HOH2193 |
| A | HOH2194 |
| A | HOH2195 |
| A | HOH2196 |
| A | HOH2197 |
| A | HOH2198 |
| A | HOH2199 |
| A | HOH2200 |
| A | HOH2201 |
| A | HOH2202 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TRS A 1259 |
| Chain | Residue |
| A | ASP17 |
| A | TYR154 |
| A | ASP157 |
| A | NAP1258 |
| A | HOH2118 |
| A | HOH2203 |
| A | HOH2204 |
| B | VAL71 |
| B | VAL79 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 1260 |
| Chain | Residue |
| A | GLU111 |
| A | HIS243 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1261 |
| Chain | Residue |
| A | ASP75 |
| A | HOH2206 |
| A | HOH2207 |
| B | HIS255 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1262 |
| Chain | Residue |
| A | HIS114 |
| A | GLU116 |
| B | HIS114 |
| B | GLU116 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1263 |
| Chain | Residue |
| A | HIS25 |
| A | ASP62 |
| A | HOH2208 |
| B | ASP3 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 1264 |
| Chain | Residue |
| A | HIS25 |
| A | HOH2209 |
| B | GLU102 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 1265 |
| Chain | Residue |
| A | GLU102 |
| B | HIS25 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 1266 |
| Chain | Residue |
| A | ASP141 |
| B | ASP139 |
| B | ZN1266 |
| site_id | BC2 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE FAD B 1257 |
| Chain | Residue |
| B | SER85 |
| B | THR125 |
| B | TYR256 |
| B | NAP1258 |
| B | HOH2048 |
| B | HOH2062 |
| B | HOH2106 |
| B | HOH2178 |
| B | HOH2180 |
| B | HOH2181 |
| B | HOH2182 |
| B | HOH2183 |
| B | HOH2184 |
| B | PHE36 |
| B | ARG50 |
| B | ALA51 |
| B | TYR52 |
| B | SER53 |
| B | TYR66 |
| B | LEU67 |
| B | VAL68 |
| B | VAL70 |
| B | TYR72 |
| B | GLY82 |
| B | LYS83 |
| B | LEU84 |
| site_id | BC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAP B 1258 |
| Chain | Residue |
| B | ALA18 |
| B | LEU19 |
| B | VAL68 |
| B | THR69 |
| B | VAL70 |
| B | VAL71 |
| B | THR123 |
| B | ALA152 |
| B | ARG153 |
| B | ASP157 |
| B | SER182 |
| B | ARG183 |
| B | ARG193 |
| B | PRO195 |
| B | ASN223 |
| B | GLN225 |
| B | MET226 |
| B | ASP229 |
| B | FAD1257 |
| B | TRS1259 |
| B | HOH2114 |
| B | HOH2186 |
| B | HOH2187 |
| B | HOH2188 |
| B | HOH2189 |
| B | HOH2190 |
| B | HOH2191 |
| B | HOH2192 |
| B | HOH2193 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TRS B 1259 |
| Chain | Residue |
| B | ASP17 |
| B | TYR154 |
| B | ASP157 |
| B | NAP1258 |
| B | HOH2193 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1260 |
| Chain | Residue |
| B | ARG135 |
| B | ARG170 |
| B | HOH2194 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 1261 |
| Chain | Residue |
| B | GLN178 |
| B | THR179 |
| B | GLY188 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1262 |
| Chain | Residue |
| A | HIS255 |
| B | ASP75 |
| B | HOH2195 |
| B | HOH2196 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1263 |
| Chain | Residue |
| A | ASP3 |
| B | HIS25 |
| B | ASP62 |
| B | HOH2197 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN B 1264 |
| Chain | Residue |
| B | GLU111 |
| B | HIS243 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 1265 |
| Chain | Residue |
| B | GLU199 |
| B | GLU236 |
| B | HOH2198 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 1266 |
| Chain | Residue |
| A | ASP139 |
| A | ZN1266 |
| B | ASP141 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN B 1267 |
| Chain | Residue |
| B | GLU172 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 1268 |
| Chain | Residue |
| B | HOH2072 |
| B | HOH2072 |
| B | HOH2159 |
| B | HOH2159 |
| B | HOH2200 |
| B | HOH2200 |
Functional Information from PROSITE/UniProt
| site_id | PS00430 |
| Number of Residues | 37 |
| Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. gsmaaagrriladwvtgkvtkvqnwtdal......................................................................................FSLTVHAP |
| Chain | Residue | Details |
| A | GLY-9-PRO27 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21306142","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XNJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21306142","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9149148","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FDR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2XNJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"9149148","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1FDR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
