2XIK

Structure of Human YSK1 (Yeast Sps1-Ste20-related Kinase 1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1293

Chain	Residue
A	ARG122
A	LYS126
A	LEU265
A	ILE270
A	HOH2146

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE J60 A 1294

Chain	Residue
A	TYR97
A	LEU98
A	ASP105
A	LYS108
A	LEU147
A	TYR287
A	HOH2147
A	ARG25
A	ILE26
A	ALA47
A	GLU96

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Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	24
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGKGSFGEVYkGidnhtkev..........VAIK

Chain	Residue	Details
A	ILE26-LYS49

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by autocatalysis","evidences":[{"source":"PubMed","id":"15037601","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9Z2W1","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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