2XED
Nocardia farcinica maleate cis-trans isomerase C194S mutant with a covalently bound succinylcysteine intermediate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0050076 | molecular_function | maleate isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0050076 | molecular_function | maleate isomerase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0050076 | molecular_function | maleate isomerase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0050076 | molecular_function | maleate isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SIN A 300 |
| Chain | Residue |
| A | PRO11 |
| A | GLN196 |
| A | ASN14 |
| A | CYS76 |
| A | LEU77 |
| A | VAL78 |
| A | TYR133 |
| A | ASN163 |
| A | ALA194 |
| A | VAL195 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SIN B 300 |
| Chain | Residue |
| B | PRO11 |
| B | ASN14 |
| B | CYS76 |
| B | LEU77 |
| B | VAL78 |
| B | TYR133 |
| B | ASN163 |
| B | ALA194 |
| B | VAL195 |
| B | GLN196 |
| B | HOH2102 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SIN C 300 |
| Chain | Residue |
| C | PRO11 |
| C | ASN14 |
| C | MET42 |
| C | CYS76 |
| C | LEU77 |
| C | VAL78 |
| C | TYR133 |
| C | ASN163 |
| C | ALA194 |
| C | VAL195 |
| C | GLN196 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SIN D 300 |
| Chain | Residue |
| D | PRO11 |
| D | ASN14 |
| D | CYS76 |
| D | LEU77 |
| D | VAL78 |
| D | TYR133 |
| D | ASN163 |
| D | ALA194 |
| D | VAL195 |
| D | GLN196 |
| D | HOH2099 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"20677745","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"20677745","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20677745","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"S-(2-succinyl)cysteine","evidences":[{"source":"PubMed","id":"20677745","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XED","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
