2XBF

Nedd4 HECT structure

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004842	molecular_function	ubiquitin-protein transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1894

Chain	Residue
A	TRP687
A	LEU696
A	GLU731
A	EDO1895
A	HOH2197

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1895

Chain	Residue
A	SER684
A	EDO1894

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1896

Chain	Residue
A	GLN712
A	ARG558
A	ARG559

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1897

Chain	Residue
A	TYR557
A	MET561
A	HIS711
A	GLN712

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 1898

Chain	Residue
A	TYR794
A	ALA800
A	HOH2148

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q62940

Chain	Residue	Details
A	GLU576

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P46935

Chain	Residue	Details
A	HIS648

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P46935

Chain	Residue	Details
A	THR670

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	VAL742

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332

Chain	Residue	Details
A	LYS747

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