2X9Q
Structure of the Mycobacterium tuberculosis protein, Rv2275, demonstrates that cyclodipeptide synthetases are related to type I tRNA-Synthetases.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016755 | molecular_function | aminoacyltransferase activity |
| A | 0016875 | molecular_function | ligase activity, forming carbon-oxygen bonds |
| B | 0005515 | molecular_function | protein binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016755 | molecular_function | aminoacyltransferase activity |
| B | 0016875 | molecular_function | ligase activity, forming carbon-oxygen bonds |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000305|PubMed:20852636 |
| Chain | Residue | Details |
| A | SER88 | |
| B | SER88 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN91 | |
| A | TYR229 | |
| A | TYR253 | |
| B | ASN91 | |
| B | TYR229 | |
| B | TYR253 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Could have a critical role in the catalytic mechanism => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN91 | |
| A | GLU233 | |
| B | ASN91 | |
| B | GLU233 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Could be involved in aa-tRNA binding => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS139 | |
| A | TYR229 | |
| B | LYS139 | |
| B | TYR229 |
