Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004018 | molecular_function | N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| A | 0009168 | biological_process | purine ribonucleoside monophosphate biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0044208 | biological_process | 'de novo' AMP biosynthetic process |
| A | 0070626 | molecular_function | (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE OXL A 1432 |
| Chain | Residue |
| A | HIS68 |
| A | SER94 |
| A | GLN259 |
| A | AMP1433 |
| A | HOH2022 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE AMP A 1433 |
| Chain | Residue |
| A | ASP69 |
| A | SER94 |
| A | THR95 |
| A | HIS141 |
| A | GLN212 |
| A | ASN276 |
| A | ARG301 |
| A | ILE303 |
| A | SER306 |
| A | ARG310 |
| A | OXL1432 |
| A | HOH2070 |
| A | ARG4 |
| A | TYR5 |
| A | ARG67 |
| A | HIS68 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE P6G A 1434 |
| Chain | Residue |
| A | ARG85 |
| A | ALA125 |
| A | LYS129 |
| A | ASN130 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1435 |
| Chain | Residue |
| A | ALA207 |
| A | GLN215 |
| A | ARG218 |
Functional Information from PROSITE/UniProt
| site_id | PS00163 |
| Number of Residues | 10 |
| Details | FUMARATE_LYASES Fumarate lyases signature. GSsaMpHKrN |
| Chain | Residue | Details |
| A | GLY261-ASN270 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"UniProtKB","id":"P0AB89","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 13 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P0AB89","evidenceCode":"ECO:0000250"}]} |
