2X6N

Human foamy virus integrase - catalytic core. Manganese-bound structure.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003676	molecular_function	nucleic acid binding
A	0015074	biological_process	DNA integration
B	0003676	molecular_function	nucleic acid binding
B	0015074	biological_process	DNA integration
C	0003676	molecular_function	nucleic acid binding
C	0015074	biological_process	DNA integration
D	0003676	molecular_function	nucleic acid binding
D	0015074	biological_process	DNA integration
E	0003676	molecular_function	nucleic acid binding
E	0015074	biological_process	DNA integration
F	0003676	molecular_function	nucleic acid binding
F	0015074	biological_process	DNA integration

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 1197

Chain	Residue
A	ASP128
A	ASP185
A	HOH2079
A	HOH2080
A	HOH2081
A	HOH2082

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MN B 1196

Chain	Residue
B	ASP128
B	ASP185
B	HOH2075

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN C 1197

Chain	Residue
C	ASP128
C	ASP185
C	HOH2044
C	HOH2045
C	HOH2046
C	HOH2047

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MN D 1196

Chain	Residue
D	ASP128
D	ASP185

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN E 1193

Chain	Residue
E	ASP128
E	ASP185
E	HOH2004
E	HOH2050
E	HOH2051
E	HOH2052

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN F 1195

Chain	Residue
F	ASP128
F	ASP185
F	HOH2033
F	HOH2034
F	HOH2035
F	HOH2036

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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