2WYH
Structure of the Streptococcus pyogenes family GH38 alpha-mannosidase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004559 | molecular_function | alpha-mannosidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006013 | biological_process | mannose metabolic process |
| A | 0009313 | biological_process | oligosaccharide catabolic process |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004559 | molecular_function | alpha-mannosidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006013 | biological_process | mannose metabolic process |
| B | 0009313 | biological_process | oligosaccharide catabolic process |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030246 | molecular_function | carbohydrate binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 902 |
| Chain | Residue |
| A | HIS13 |
| A | ASP15 |
| A | ASP125 |
| A | HIS351 |
| A | HOH2010 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 903 |
| Chain | Residue |
| B | HIS378 |
| B | TYR379 |
| B | LYS382 |
| A | GLN24 |
| A | ARG28 |
| A | HOH2467 |
| A | HOH2468 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 904 |
| Chain | Residue |
| A | ARG102 |
| A | LEU105 |
| A | LEU338 |
| A | ARG339 |
| A | TRP342 |
| A | HOH2208 |
| A | HOH2469 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 905 |
| Chain | Residue |
| A | THR201 |
| A | GLU202 |
| A | HOH2114 |
| A | HOH2470 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 906 |
| Chain | Residue |
| A | PRO479 |
| A | LYS480 |
| A | ARG481 |
| A | HOH2277 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 907 |
| Chain | Residue |
| A | ARG546 |
| A | ARG563 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 908 |
| Chain | Residue |
| A | THR686 |
| A | ASP687 |
| A | HIS688 |
| A | HOH2349 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 909 |
| Chain | Residue |
| A | ARG310 |
| A | GLU371 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 902 |
| Chain | Residue |
| B | HIS13 |
| B | ASP15 |
| B | ASP125 |
| B | HIS351 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TRS B 903 |
| Chain | Residue |
| A | HIS378 |
| A | TYR379 |
| A | LYS382 |
| A | HOH2225 |
| B | GLN24 |
| B | ARG28 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 904 |
| Chain | Residue |
| B | THR686 |
| B | ASP687 |
| B | HIS688 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 905 |
| Chain | Residue |
| B | ASP619 |
| B | LYS620 |
| B | SER640 |
| B | GLN641 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 906 |
| Chain | Residue |
| B | PRO479 |
| B | LYS480 |
| B | ARG481 |
| B | HOH2260 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 907 |
| Chain | Residue |
| B | ARG660 |
| B | TYR782 |
| B | GLY802 |
| B | HOH2397 |
| B | HOH2445 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 908 |
| Chain | Residue |
| B | ARG102 |
| B | ILE106 |
| B | LEU338 |
| B | ARG339 |
| B | TRP342 |
| B | HOH2186 |
