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Crystal Structure of Methylmalonic Acidemia Type A Protein

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005525molecular_functionGTP binding
B0003924molecular_functionGTPase activity
B0005525molecular_functionGTP binding
C0003924molecular_functionGTPase activity
C0005525molecular_functionGTP binding
D0003924molecular_functionGTPase activity
D0005525molecular_functionGTP binding
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE 2PE A 500
ChainResidue
APRO141
AALA143
AASP237
AASP258
AGLN346
ALEU355

site_idAC2
Number of Residues12
DetailsBINDING SITE FOR RESIDUE GDP A 600
ChainResidue
ALYS156
ASER157
ATHR158
ALYS290
AASP292
ASER328
AALA329
AARG330
AHOH2012
AGLY153
AALA154
AGLY155

site_idAC3
Number of Residues12
DetailsBINDING SITE FOR RESIDUE GDP B 600
ChainResidue
BPRO151
BGLY153
BALA154
BGLY155
BLYS156
BSER157
BTHR158
BASP292
BSER328
BALA329
BARG330
BHOH2020

site_idAC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE 2PE C 500
ChainResidue
CPRO141
CALA143
CPHE144
CARG170
CGLY171
CHIS172
CASP237
CGLN346

site_idAC5
Number of Residues13
DetailsBINDING SITE FOR RESIDUE GDP C 600
ChainResidue
CGLY153
CALA154
CGLY155
CLYS156
CSER157
CTHR158
CLYS290
CASP292
CSER328
CALA329
CARG330
CHOH2014
CHOH2015

site_idAC6
Number of Residues8
DetailsBINDING SITE FOR RESIDUE 2PE D 500
ChainResidue
DGLU82
DPRO141
DPHE144
DARG170
DHIS172
DASP237
DGLN346
DHOH2028

site_idAC7
Number of Residues13
DetailsBINDING SITE FOR RESIDUE GDP D 600
ChainResidue
DGLY153
DALA154
DGLY155
DLYS156
DSER157
DTHR158
DLYS290
DASP292
DSER328
DALA329
DARG330
DHOH2029
DHOH2030

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:20876572
ChainResidueDetails
AGLY150
ASER328
BGLY150
BSER328
CGLY150
CSER328
DGLY150
DSER328

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:20876572, ECO:0000269|PubMed:28497574
ChainResidueDetails
AASP292
BASP292
CASP292
DASP292

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PDB entries from 2024-10-30

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