2WUT

Crystal structure of human myelin protein P2 in complex with palmitate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005504	molecular_function	fatty acid binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008289	molecular_function	lipid binding
A	0015485	molecular_function	cholesterol binding
A	0015908	biological_process	fatty acid transport
A	0043209	cellular_component	myelin sheath
A	0061024	biological_process	membrane organization
A	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PLM A 1134

Chain	Residue
A	MET20
A	HOH2272
A	GLY33
A	SER55
A	ALA75
A	ASP76
A	ARG106
A	ARG126
A	TYR128
A	HOH2151

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1135

Chain	Residue
A	LYS37
A	THR56

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1136

Chain	Residue
A	ASN15
A	ASP18
A	HOH2062
A	HOH2273
A	HOH2274
A	HOH2275

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Functional Information from PROSITE/UniProt

site_id	PS00214
Number of Residues	18
Details	FABP Cytosolic fatty-acid binding proteins signature. GTWkLvsSeNFDdYMKAL

Chain	Residue	Details
A	GLY6-LEU23

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:20421974, ECO:0007744|PDB:2WUT

Chain	Residue	Details
A	ARG106
A	ARG126

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylserine => ECO:0000269|PubMed:6183401

Chain	Residue	Details
A	SER1

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