2WSX
Crystal Structure of Carnitine Transporter from Escherichia coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009437 | biological_process | carnitine metabolic process |
| A | 0015226 | molecular_function | carnitine transmembrane transporter activity |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0015879 | biological_process | carnitine transport |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0044667 | molecular_function | (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity |
| A | 0071705 | biological_process | nitrogen compound transport |
| A | 1900749 | biological_process | (R)-carnitine transport |
| A | 1900751 | biological_process | 4-(trimethylammonio)butanoate transport |
| A | 1902270 | biological_process | (R)-carnitine transmembrane transport |
| A | 1902603 | biological_process | carnitine transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009437 | biological_process | carnitine metabolic process |
| B | 0015226 | molecular_function | carnitine transmembrane transporter activity |
| B | 0015297 | molecular_function | antiporter activity |
| B | 0015879 | biological_process | carnitine transport |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0044667 | molecular_function | (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity |
| B | 0071705 | biological_process | nitrogen compound transport |
| B | 1900749 | biological_process | (R)-carnitine transport |
| B | 1900751 | biological_process | 4-(trimethylammonio)butanoate transport |
| B | 1902270 | biological_process | (R)-carnitine transmembrane transport |
| B | 1902603 | biological_process | carnitine transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009437 | biological_process | carnitine metabolic process |
| C | 0015226 | molecular_function | carnitine transmembrane transporter activity |
| C | 0015297 | molecular_function | antiporter activity |
| C | 0015879 | biological_process | carnitine transport |
| C | 0016020 | cellular_component | membrane |
| C | 0022857 | molecular_function | transmembrane transporter activity |
| C | 0044667 | molecular_function | (R)-carnitine:4-(trimethylammonio)butanoate antiporter activity |
| C | 0071705 | biological_process | nitrogen compound transport |
| C | 1900749 | biological_process | (R)-carnitine transport |
| C | 1900751 | biological_process | 4-(trimethylammonio)butanoate transport |
| C | 1902270 | biological_process | (R)-carnitine transmembrane transport |
| C | 1902603 | biological_process | carnitine transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NM2 A 1504 |
| Chain | Residue |
| A | TRP142 |
| A | TRP323 |
| A | TYR327 |
| A | MET331 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NM2 A 1505 |
| Chain | Residue |
| A | GLY311 |
| A | PHE312 |
| A | GLY315 |
| A | LEU469 |
| A | GLN473 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NM2 B 1504 |
| Chain | Residue |
| B | TRP142 |
| B | TRP323 |
| B | TYR327 |
| B | MET331 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NM2 B 1505 |
| Chain | Residue |
| B | TYR114 |
| B | GLY311 |
| B | PHE312 |
| B | GLY315 |
| B | GLN473 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NM2 C 1504 |
| Chain | Residue |
| C | TRP142 |
| C | TRP323 |
| C | TYR327 |
| C | MET331 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NM2 C 1505 |
| Chain | Residue |
| C | TYR114 |
| C | GLY311 |
| C | PHE312 |
| C | GLY315 |
| C | LEU469 |
| C | GLN473 |
Functional Information from PROSITE/UniProt
| site_id | PS01303 |
| Number of Residues | 10 |
| Details | BCCT BCCT family of transporters signature. GWTVfYWaWW |
| Chain | Residue | Details |
| A | GLY315-TRP324 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 726 |
| Details | Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"20357772","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3HFX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 378 |
| Details | Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"20357772","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3HFX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 261 |
| Details | Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"20357772","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3HFX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20829798","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WSX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 15 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20357772","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3HFX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
